CFTR and congenital bilateral absence of the vas deferens (CBAVD)

Congenital bilateral absence of the vas deferens (CBAVD) is a condition present from birth in which the tubes that normally carry sperm from the testes are missing on both sides, causing obstructive azoospermia with normal sperm production in the testis. It is strongly linked to changes in the CFTR gene, the same gene responsible for cystic fibrosis, though many men with CBAVD have only mild or no other CFTR-related symptoms. Men diagnosed with CBAVD, and their partners, are usually offered CFTR gene testing and genetic counselling, because if both partners carry a CFTR gene change there is a chance of cystic fibrosis or CBAVD in a child. Fertility is usually achieved through surgical sperm retrieval directly from the epididymis or testis combined with ICSI, since the blockage itself cannot be corrected in most cases. This is general information about India's ART and surrogacy framework and is not personalised legal advice. India legal information last reviewed: 9 September 2026.

Also known as: CFTR, CBAVD, congenital absence of vas deferens

Last reviewed: 9 September 2026. Written by the Antega Editorial Team. General information only — always follow the advice of your own clinic, doctor or pharmacist.