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A–Z Fertility Glossary

415 fertility terms explained in plain language.

415 terms

A

Additional or unexpected treatment costs
Costs & access

Costs that can arise mid-treatment and are easy to miss when comparing headline quotes.

Adenomyosis
Female fertility

A condition where endometrial-type tissue grows within the muscular wall of the uterus, causing pain and heavy bleeding.

Adhesiolysis
Female fertility

Surgery to divide scar tissue (adhesions) that binds pelvic organs together.

Advanced sperm selection add-ons (PICSI, IMSI, MACS, microfluidic selection)
IVF treatment

Extra laboratory methods for choosing sperm before ICSI, offered at added cost with limited proven benefit for most patients.

Age and eligibility conditions for accessing ART
India ART regulation

Who may access ART treatment in India, and any age limits, are set by the Act and Rules and can change.

Agonist protocol
IVF treatment

An IVF stimulation protocol using a GnRH agonist medicine to suppress the pituitary before stimulation.

Air pollution and fertility
Lifestyle & preconception

Exposure to high air pollution levels is being studied as a possible factor affecting fertility.

Alcohol and fertility
Lifestyle & preconception

Higher alcohol intake is linked to reduced fertility and is best discussed openly with your care team.

Altruistic surrogacy
Surrogacy

The only form of surrogacy lawful in India: no payment to the surrogate beyond medical expenses and insurance.

Amenorrhoea
Female fertility

The absence of menstrual periods, which can be a normal life stage or a sign of an underlying condition.

Anejaculation
Male fertility

The inability to ejaculate semen, whether during intercourse, masturbation or both.

Anembryonic pregnancy
Pregnancy loss

A gestational sac that develops without an embryo forming inside it.

Aneuploid
Genetics & PGT

Having an abnormal number of chromosomes (extra or missing).

Anovulation
Fertility basics

The absence of ovulation in a menstrual cycle.

Anovulatory infertility
Female fertility

Infertility caused by absent or infrequent ovulation, one of the most common and treatable causes.

Antagonist protocol
IVF treatment

An IVF stimulation protocol using a GnRH antagonist medicine to prevent premature ovulation.

Anti-Müllerian hormone (AMH)
Fertility testing

A blood test that estimates how many eggs remain in the ovaries.

Anti-tubercular treatment (ATT)
Infections

The multi-drug course used to treat confirmed tuberculosis, prescribed under NTEP protocols.

Antioxidant supplements in fertility
Lifestyle & preconception

Supplements such as CoQ10, myo-inositol and DHEA are sometimes used, but evidence is mixed and they are not a cure for infertility.

Antiphospholipid syndrome (APS)
Pregnancy loss

An autoimmune condition linked to blood clotting and pregnancy loss, diagnosed by specific antibody blood tests.

Antral follicle count (AFC)
Fertility testing

An ultrasound count of small resting follicles used to estimate ovarian reserve.

Appropriate Authority
India ART regulation

The state or union territory official responsible for registering and inspecting ART and surrogacy clinics.

ART (Regulation) Act, 2021
India ART regulation

The Indian law governing assisted reproductive technology clinics and ART banks.

ART (Regulation) Rules
India ART regulation

The detailed rules made under the ART Act, updated by later amendments including in 2026.

ART bank
India ART regulation

A registered organisation that collects, screens and supplies donor gametes in India.

ART bank as a gamete supplier
Donor conception

The registered ART bank is the only lawful source of donor eggs, sperm and embryos in India.

ART clinic
India ART regulation

A facility offering assisted reproduction procedures, which must be registered under the ART Act.

Asherman syndrome
Female fertility

Scar tissue (adhesions) inside the uterine cavity, often after surgery or infection, which can affect periods and fertility.

Assisted hatching and embryo glue
IVF treatment

Laboratory add-ons that create an opening in the zona pellucida, or add a substance to the transfer fluid, with uncertain overall benefit.

Assisted oocyte activation (AOA)
Embryology

A laboratory technique, usually with calcium ionophore, used alongside ICSI for specific egg-activation problems.

Assisted reproductive technology (ART)
India ART regulation

Medical techniques used to help conception, such as IVF, ICSI and IUI, regulated by Indian law.

Asthenozoospermia
Male fertility

Reduced sperm motility, meaning fewer sperm than usual are moving actively.

Ayurveda and traditional medicine
Lifestyle & preconception

Traditional Indian medicine systems some people use alongside fertility care; always tell your treatment team.

Azoospermia
Male fertility

No sperm found in the ejaculate on semen analysis, confirmed on at least two occasions.

B

C

Cabergoline
Fertility medicines

A medicine used to lower high prolactin levels, which can otherwise disrupt ovulation.

Caesarean scar defect
Female fertility

A gap or niche in the uterine wall at a previous caesarean scar, which can cause bleeding or affect fertility.

Caffeine and fertility
Lifestyle & preconception

High caffeine intake is sometimes linked to reduced fertility; moderation is generally advised.

Cancelled IVF cycle
IVF treatment

An IVF cycle stopped before egg retrieval or transfer because of a monitoring finding during treatment.

Cardiac activity
Pregnancy after treatment

The flickering heartbeat seen on ultrasound, usually from around six weeks of pregnancy.

Carrier and carrier couple
Genetics & PGT

A person with one copy of a gene change for a recessive condition, usually without symptoms.

Carrier screening
Genetics & PGT

Testing to check whether a person carries a gene change for a recessive condition.

CDSCO
Fertility medicines

India's central medicines regulator.

Certificate of eligibility
Surrogacy

A certificate confirming a commissioning couple or surrogate meets the legal conditions to proceed with surrogacy.

Certificate of essentiality
Surrogacy

A certificate confirming a commissioning couple's medical need for surrogacy, required before starting the process.

Cervical insufficiency
Pregnancy loss

A weakness of the cervix that can lead to painless dilation and pregnancy loss in the second trimester.

Cervical stenosis
Female fertility

Narrowing of the cervical canal that can make procedures such as embryo transfer more difficult.

CFTR and congenital bilateral absence of the vas deferens (CBAVD)
Genetics & PGT

A genetic condition where both vas deferens are missing from birth, causing obstructive azoospermia.

Chlamydia
Infections

A common bacterial STI that often has no symptoms but can silently damage the fallopian tubes.

Chromopertubation
Fertility testing

A test done during laparoscopy that uses dye to check if the fallopian tubes are open.

Chromosome abnormality (trisomy and monosomy)
Genetics & PGT

A change in the usual number or structure of chromosomes.

Chronic endometritis
Female fertility

Persistent low-grade inflammation of the uterine lining, sometimes linked to implantation failure.

Cleavage-stage embryo
Embryology

An early embryo, usually seen on Day 2 or Day 3, made up of a small number of dividing cells.

Clinical pregnancy
Pregnancy after treatment

A pregnancy confirmed by ultrasound, with at least a gestational sac seen inside the uterus.

Clomiphene citrate
Fertility medicines

An oral medicine used to stimulate ovulation, particularly in women with PCOS.

Commercial surrogacy
Surrogacy

Paying a surrogate beyond permitted expenses: prohibited in India under the Surrogacy Act.

Commissioning couple
Surrogacy

A married couple who use their own or donor gametes with a gestational surrogate under the Surrogacy Act.

Compaction and morula
Embryology

The stage, usually around Day 4, when embryo cells merge together to form a solid ball called a morula.

Conception
Fertility basics

The point at which fertilisation results in a viable pregnancy.

Consanguinity
Genetics & PGT

A marriage or partnership between blood relatives, relevant to recessive genetic conditions.

Conventional in vitro fertilisation (IVF)
Embryology

Mixing eggs and prepared sperm in a dish so fertilisation can happen without injection.

Corpus luteum
Anatomy & hormones

The temporary hormone-producing structure formed after ovulation.

Corpus luteum cyst
Female fertility

A cyst that forms from the structure left behind after an egg is released.

Cryopreservation
Fertility preservation

Freezing and storing eggs, sperm or embryos at very low temperature for later use.

Cryptorchidism
Anatomy & hormones

A testis that has not descended fully into the scrotum, usually identified in infancy.

Cryptozoospermia
Male fertility

Extremely few sperm found in the ejaculate, only visible after concentrating the sample.

Cycle cancellation
IUI & ovulation treatment

Stopping a treatment cycle before insemination, egg collection or transfer due to a monitoring finding.

D

Dehydroepiandrosterone sulphate (DHEAS)
Anatomy & hormones

An adrenal androgen sometimes tested when androgen excess is suspected.

Dermoid cyst
Female fertility

A benign ovarian cyst containing tissue such as hair, skin or fat, present from birth.

Difficult embryo transfer
IVF treatment

A transfer procedure that is technically more challenging than usual, for example due to the shape or position of the uterus or cervix.

Diminished ovarian reserve (DOR)
Fertility testing

A lower than expected number of remaining eggs for a woman's age.

Distal tubal obstruction
Female fertility

Blockage near the tube's outer, fimbrial end, close to the ovary.

District Medical Board
Surrogacy

A district-level board that certifies medical facts needed for surrogacy, such as the certificate of essentiality.

Dominant follicle
Anatomy & hormones

The largest, lead follicle that matures and releases an egg during a natural cycle.

Donor conception
Donor conception

Conceiving using donor eggs, donor sperm or donor embryos supplied through a registered ART bank.

Donor confidentiality in India
India ART regulation

How donor identity is protected and recorded under India's ART framework.

Donor egg
Donor conception

An egg provided by a screened donor through a registered ART bank for use in another person's treatment.

Donor eligibility under Indian law
India ART regulation

The statutory age, health and prior-donation limits a person must meet to donate eggs or sperm in India.

Donor embryo
Donor conception

An embryo, created from donated eggs and sperm or donated by another couple, used for embryo transfer.

Donor insemination
Donor conception

IUI performed using sperm from a registered sperm bank donor rather than a partner.

Donor screening
Donor conception

Medical, genetic and infectious-disease tests every gamete donor must pass before donation is accepted.

Donor sperm
Donor conception

Sperm provided by a screened donor through a registered ART bank for use in fertility treatment.

Donor treatment cost
Costs & access

Costs linked to using donor eggs or sperm, on top of standard IVF fees.

Donor-conceived person
Donor conception

A person born from treatment using donor eggs, donor sperm or a donor embryo.

Double embryo transfer (DET)
IVF treatment

Transferring two embryos in a single cycle, which raises the chance of a multiple pregnancy.

Duchenne muscular dystrophy
Genetics & PGT

An inherited, X-linked condition causing progressive muscle weakness, mainly in boys.

DuoStim
IVF treatment

Two ovarian stimulations and egg retrievals performed within a single menstrual cycle.

Dysmenorrhoea
Female fertility

Painful periods, which can be a normal variant or a sign of an underlying condition such as endometriosis.

E

Ectopic pregnancy
Pregnancy loss

A pregnancy developing outside the uterus, most often in a fallopian tube; a medical emergency if it ruptures.

Egg freezing (oocyte cryopreservation)
Fertility preservation

Collecting and freezing unfertilised eggs to preserve the option of pregnancy later.

Egg quality
Female fertility

How likely an egg is to fertilise and develop into a healthy embryo.

Egg retrieval
IVF treatment

The minor procedure to collect mature eggs from the ovaries, usually under sedation.

Ejaculatory duct obstruction
Male fertility

A blockage of the short ducts that carry sperm and fluid into the urethra during ejaculation.

Embryo arrest
Embryology

When an embryo stops dividing during laboratory culture before reaching the intended stage.

Embryo biopsy (trophectoderm biopsy)
Genetics & PGT

Removing a few cells from an embryo for genetic testing before transfer.

Embryo cryopreservation
Fertility preservation

Freezing embryos created by IVF/ICSI for use in a later frozen embryo transfer.

Embryo culture
Embryology

Growing embryos in the laboratory incubator between fertilisation and transfer or freezing.

Embryo fragmentation and multinucleation
Embryology

Two appearance features embryologists note during grading: cell fragments, and cells with more than one nucleus.

Embryo freezing
Fertility preservation

Vitrifying and storing embryos, usually at the blastocyst stage, for use in a later cycle.

Embryo grading
Embryology

A description of an embryo's laboratory appearance on a given day, not a guarantee of pregnancy or its absence.

Embryo storage and annual storage fee
Fertility preservation

Ongoing storage of frozen embryos at a registered clinic or ART bank, usually with a recurring fee and consent renewal.

Embryo storage fee
Costs & access

The recurring charge for freezing and storing embryos, usually billed annually.

Embryo transfer (ET)
IVF treatment

The procedure of placing an embryo into the uterus; the procedure itself is not the same as implantation.

Embryo warming
Fertility preservation

The process of bringing a vitrified embryo back to body temperature before transfer, and checking it survives.

Embryonic pole (fetal pole)
Pregnancy after treatment

The first visible outline of the developing embryo, seen on ultrasound inside the gestational sac.

Employer fertility benefit
Costs & access

Workplace schemes that may help with fertility treatment costs or leave, where offered.

Empty follicle syndrome
IVF treatment

A rare situation where no eggs are found in the follicles at egg retrieval despite apparently normal stimulation.

Endometrial biopsy
Fertility testing

A procedure to take a small sample of the uterine lining for testing.

Endometrial hyperplasia
Female fertility

Thickening of the uterine lining due to excess growth of endometrial cells, sometimes needing treatment before pregnancy attempts.

Endometrial polyp
Female fertility

A small growth of endometrial tissue projecting into the uterine cavity, which can affect implantation.

Endometrial receptivity
IVF treatment

The uterine lining's readiness to allow an embryo to implant during a specific window in the cycle.

Endometrial tuberculosis
Infections

Genital tuberculosis affecting the uterine lining, which can affect implantation.

Endometrioma
Female fertility

A cyst on the ovary formed by endometriosis tissue, sometimes called a 'chocolate cyst'.

Endometriosis
Female fertility

A condition where tissue similar to the womb lining grows outside the uterus, often causing pain and sometimes infertility.

Endometrium
Anatomy & hormones

The uterine lining, where an embryo implants.

Erectile dysfunction
Male fertility

Difficulty achieving or maintaining an erection sufficient for intercourse.

Euploid
Genetics & PGT

Having the normal expected number of chromosomes.

Excessive ovarian response
IVF treatment

A larger than expected number of follicles growing during ovarian stimulation.

F

Failed fertilisation
Embryology

When none, or very few, of the collected eggs show normal fertilisation.

Fallopian tube
Anatomy & hormones

The paired tubes that carry the egg from the ovary to the uterus, where fertilisation happens.

Fecundability
Fertility basics

The chance of conceiving in a single menstrual cycle.

Female genital tuberculosis (FGTB)
Infections

Tuberculosis affecting the female reproductive organs, a recognised cause of infertility in India.

Fertile window
Fertility basics

The days each cycle when intercourse is most likely to lead to pregnancy.

Fertilisation
Fertility basics

The fusion of egg and sperm to form an early embryo.

Fertilisation check
Embryology

The laboratory step, usually the morning after egg collection, that confirms whether eggs have fertilised.

Fertilisation failure
IVF treatment

When none of the eggs collected fertilise during an IVF or ICSI cycle, despite the procedure being carried out normally.

Fertility
Fertility basics

The natural ability to conceive and carry a pregnancy.

Fertility preservation
Fertility preservation

Freezing eggs, sperm, embryos or ovarian tissue to protect the chance of a future biological child.

Fertility preservation before gender-affirming treatment
Fertility preservation

Freezing eggs, sperm or embryos before hormone therapy or surgery that may affect future fertility.

Folic acid
Lifestyle & preconception

A B-vitamin recommended before and during early pregnancy to reduce the risk of neural tube defects.

Follicle
Anatomy & hormones

A fluid-filled sac in the ovary that contains and matures an egg.

Follicle-stimulating hormone (FSH)
Anatomy & hormones

The pituitary hormone that drives egg and sperm development.

Follicular monitoring
Fertility testing

Repeated ultrasound scans that track follicle growth during a treatment cycle.

Follicular phase
Fertility basics

The first half of the menstrual cycle, when an egg matures.

Fragile X premutation
Genetics & PGT

An intermediate genetic change linked to premature ovarian insufficiency and fragile X syndrome risk.

Freeze-all cycle
IVF treatment

An IVF cycle in which all embryos are frozen rather than transferred fresh, for transfer in a later cycle.

Fresh embryo transfer
IVF treatment

Transferring an embryo in the same cycle in which the eggs were collected, without freezing.

Frozen embryo transfer (FET)
IVF treatment

Transferring an embryo that was previously vitrified and stored, after warming it in a later cycle.

Frozen embryo transfer fee
Costs & access

The separate charge for thawing and transferring a previously frozen embryo.

G

Gamete donor
Donor conception

A person who provides eggs or sperm for someone else's fertility treatment through an ART bank.

Genetic counselling
Genetics & PGT

Specialist support to understand genetic test results and reproductive options.

Gestational age and pregnancy dating after IVF
Pregnancy after treatment

How pregnancy weeks are counted after IVF, using the embryo transfer date rather than a last period.

Gestational sac
Pregnancy after treatment

The fluid-filled sac seen on ultrasound that is usually the first visible sign of a pregnancy in the uterus.

Gestational surrogacy
Surrogacy

Surrogacy in which the surrogate has no genetic link to the child, as required under Indian law.

GnRH agonist
Fertility medicines

A medicine that initially stimulates and then suppresses the pituitary gland's hormone signals during IVF.

GnRH antagonist
Fertility medicines

A medicine that quickly blocks the pituitary hormone surge to prevent premature ovulation during IVF.

Gonadotoxic treatment
Fertility preservation

Chemotherapy, radiotherapy or other treatment that can damage egg or sperm production.

Gonadotropin
Fertility medicines

A hormone that acts on the ovaries or testes to drive reproduction.

Gonadotropins
Fertility medicines

Injectable hormones used to stimulate the ovaries to grow follicles during fertility treatment.

Gonorrhoea
Infections

A bacterial STI that can cause pelvic inflammatory disease and tubal damage if untreated.

Grief after pregnancy loss
Pregnancy loss

The emotional impact of losing a pregnancy at any stage, and why acknowledging it matters.

H

Haemoglobinopathy
Genetics & PGT

A group of inherited disorders affecting the structure or production of haemoglobin.

Haemophilia
Genetics & PGT

An inherited bleeding disorder, usually X-linked, affecting blood clotting.

Haemorrhagic cyst
Female fertility

An ovarian cyst that has bled internally, usually a self-resolving functional cyst.

Hatching blastocyst
Embryology

A blastocyst that is breaking out of its outer shell, a step that normally happens before implantation.

Health insurance for fertility care in India
Costs & access

How Indian health insurance policies do or do not cover fertility investigations and treatment.

Heavy menstrual bleeding
Female fertility

Menstrual bleeding that is heavier or longer than typical, sometimes linked to fibroids, polyps, or hormonal causes.

Hepatitis B
Infections

A viral liver infection routinely screened for before fertility treatment in India.

Hepatitis C
Infections

A viral liver infection screened for before fertility treatment in India.

Heterotopic pregnancy
Pregnancy loss

A rare situation where a pregnancy inside the uterus and an ectopic pregnancy occur at the same time.

Hirsutism
Female fertility

Excess coarse, dark hair growth in a male pattern in women, often linked to raised androgens.

HIV
Infections

A virus affecting the immune system; India's ART framework requires HIV screening before fertility treatment.

HLA matching and PGT-HLA
Genetics & PGT

Testing embryos for tissue-type matching to a sibling, tightly restricted and rarely used.

Human menopausal gonadotropin (hMG)
Fertility medicines

An injectable fertility medicine containing both FSH and LH activity, used in ovarian stimulation.

Hydrocele
Anatomy & hormones

A fluid-filled swelling around the testis that is usually separate from fertility problems.

Hydrosalpinx
Female fertility

A fallopian tube blocked and swollen with fluid, usually from past infection or damage.

Hyperandrogenism
Female fertility

Higher-than-normal levels or effects of male-type hormones in women.

Hyperprolactinaemia
Anatomy & hormones

A persistently raised blood prolactin level.

Hyperthyroidism
Fertility testing

An overactive thyroid gland, which can disrupt menstrual cycles and needs treatment before pregnancy.

Hypogonadism
Anatomy & hormones

Reduced production of sex hormones by the ovaries or testes.

Hypogonadotropic hypogonadism
Anatomy & hormones

Low testosterone and sperm production due to insufficient pituitary hormone signalling.

Hypothalamic amenorrhoea
Female fertility

Absent periods caused by the brain reducing reproductive hormone signals, often linked to stress, low weight, or intense exercise.

Hypothyroidism
Fertility testing

An underactive thyroid gland, which can disrupt ovulation and menstrual regularity if untreated.

Hysterosalpingography (HSG)
Fertility testing

An X-ray test that checks whether the fallopian tubes are open using a dye.

Hysteroscopy
Fertility testing

A procedure using a thin camera through the cervix to view and treat the uterine cavity.

I

Implantation
Fertility basics

When an embryo attaches to and embeds in the uterine lining.

Implantation window
Embryology

The short period when the endometrium is receptive to an embryo; not something symptoms can reliably reveal.

In vitro fertilisation (IVF)
IVF treatment

Fertility treatment where eggs and sperm are combined outside the body to create embryos.

Inclusive family-building terms in India
Lifestyle & preconception

Terms used by single people, LGBTQ+ people and others building a family, and a note on what is legally available in India.

Infection screening before ART
India ART regulation

The mandatory pre-treatment infection tests required under India's ART framework.

Infertility
Fertility basics

Not conceiving after a year of regular unprotected intercourse.

Informed consent under the ART Act
India ART regulation

The written consent that patients, donors and clinics must complete before ART procedures under Indian law.

Inheritance patterns (autosomal recessive, autosomal dominant, X-linked)
Genetics & PGT

The different ways genetic conditions can pass from parents to children.

Inhibin B
Anatomy & hormones

A hormone marker of ovarian follicle activity, less commonly used than AMH.

Injection pen
Fertility medicines

A pre-filled or refillable pen-style device used to give some fertility medicines as measured injections.

Insulin resistance
Female fertility

Reduced sensitivity to insulin, closely linked with PCOS and fertility.

Intending couple
India ART regulation

A married couple who intend to undergo ART treatment such as IVF using their own or donor gametes.

Intending woman
India ART regulation

A woman who intends to undergo ART treatment on her own under the conditions set by the ART Act and Rules.

Intermenstrual bleeding
Female fertility

Bleeding or spotting between expected menstrual periods, which should be evaluated by a clinician.

Interstitial and Caesarean-scar pregnancy
Pregnancy loss

Two uncommon but higher-risk forms of ectopic pregnancy that implant in the tube's uterine end or a previous C-section scar.

Intracytoplasmic sperm injection (ICSI)
Embryology

A laboratory technique that injects a single sperm directly into an egg to assist fertilisation.

Intramural fibroid
Female fertility

A fibroid located within the muscular wall of the uterus, not distorting the cavity in most cases.

Intramuscular injection
Fertility medicines

A method of giving medicine as an injection into muscle, used for some fertility medicines.

Intrauterine insemination (IUI)
IUI & ovulation treatment

Placing washed, concentrated sperm directly into the uterus around ovulation.

IRDAI
Costs & access

India's insurance regulator.

Iron and iron-deficiency anaemia
Lifestyle & preconception

Iron is needed for healthy blood; deficiency (anaemia) is common in India and worth checking before conception.

IVF cost in India
Costs & access

What an IVF cycle in India typically covers, and what is usually quoted separately.

IVF cycle
IVF treatment

The full sequence of steps in one attempt at IVF treatment, from stimulation to pregnancy test.

IVF success rate
Costs & access

Statistics such as live birth rate describe outcomes across many patients, not a personal prediction.

K

L

M

Male-factor infertility
Male fertility

When sperm-related or male reproductive tract factors contribute to a couple not conceiving.

Mature and immature oocytes
Embryology

Mature eggs (MII) can be fertilised; immature eggs (MI or GV stage) usually cannot without further development.

Medication cost
Costs & access

The cost of stimulation and support medicines, which is separate from most package quotes.

Medication reconstitution
Fertility medicines

The process of mixing a powdered fertility medicine with a liquid before it can be injected.

Menopause and perimenopause
Female fertility

The natural, permanent end of periods and the transition years leading up to it.

Menstrual cycle
Fertility basics

The monthly hormonal cycle that prepares the body for pregnancy.

Metabolic syndrome
Female fertility

A cluster of insulin resistance, abdominal weight gain, and blood pressure/lipid changes often seen with PCOS.

Metformin
Fertility medicines

A medicine that improves insulin sensitivity, sometimes used alongside fertility treatment in PCOS.

Microdissection TESE (micro-TESE)
Male fertility

A specialised microsurgical technique to search testicular tissue for sperm in difficult cases.

Mild and minimal stimulation IVF
IVF treatment

IVF approaches using lower doses of stimulation medicine to retrieve fewer eggs with fewer side effects.

Miscarriage
Pregnancy loss

The loss of a pregnancy before it can survive independently, usually before twenty weeks.

Missed miscarriage
Pregnancy loss

A pregnancy that has stopped developing but has not yet caused bleeding or been passed naturally.

Monitoring scan
IVF treatment

Ultrasound scans during ovarian stimulation to track follicle growth and endometrial thickness.

Monogenic disorder
Genetics & PGT

A health condition caused by a change in a single gene.

Mosaic embryo
Genetics & PGT

An embryo with a mixture of chromosomally normal and abnormal cells.

MRKH syndrome
Female fertility

A congenital condition where the uterus and upper vagina do not develop, though ovaries are usually normal.

Müllerian anomaly
Female fertility

A congenital variation in the shape of the uterus, fallopian tubes, cervix, or upper vagina present from birth.

Multiple pregnancy after fertility treatment
Pregnancy after treatment

A pregnancy with more than one baby, which carries higher health risks for both mother and babies.

Multiple-follicle development
IUI & ovulation treatment

When ovulation-inducing medicines stimulate more than the intended number of mature follicles.

Mycobacterial culture
Fertility testing

Growing a sample in the lab to confirm active tuberculosis, considered a more definitive TB test.

Myomectomy
Female fertility

Surgery to remove uterine fibroids while preserving the uterus.

N

O

Obstructive azoospermia (OA)
Male fertility

No sperm in the ejaculate because of a blockage, even though sperm production is normal.

Occupational and environmental exposure
Lifestyle & preconception

Workplace or environmental exposure to certain chemicals or heat may affect fertility in some settings.

Oestradiol
Anatomy & hormones

The main oestrogen hormone that reflects follicle growth and prepares the uterine lining.

Oestradiol support in frozen embryo transfer cycles
Fertility medicines

Oestrogen medicine used to prepare the uterine lining before a medicated frozen embryo transfer.

Oligo-ovulation (irregular ovulation)
Fertility basics

Infrequent or irregular ovulation, rather than complete absence of it.

Oligoasthenoteratozoospermia (OAT)
Male fertility

A combination of low sperm count, reduced motility and reduced typical shape together.

Oligomenorrhoea
Female fertility

Infrequent menstrual periods, usually occurring more than 35 days apart, often reflecting irregular ovulation.

Oligozoospermia
Male fertility

A sperm concentration below the standard reference range on semen analysis.

Oncofertility
Fertility preservation

The field connecting cancer care with fertility preservation options before treatment starts.

Ongoing pregnancy
Pregnancy after treatment

A pregnancy that continues past the point of highest early loss risk, usually assessed around twelve weeks.

Oocyte
Anatomy & hormones

The medical term for an egg cell.

Orchitis and epididymitis
Infections

Inflammation of the testis or epididymis, often from infection, that can affect sperm quality.

Ovarian cyst (simple, functional and follicular)
Female fertility

Fluid-filled sacs on the ovary, most often harmless and linked to the normal cycle.

Ovarian cystectomy
Female fertility

Surgery to remove an ovarian cyst while preserving the rest of the ovary.

Ovarian drilling
IUI & ovulation treatment

A laparoscopic procedure that creates small punctures in the ovary to help ovulation in PCOS.

Ovarian hyperstimulation syndrome (OHSS)
IVF treatment

An exaggerated ovarian response to fertility medicines causing swelling, fluid shifts and, rarely, serious illness.

Ovarian reserve
Fertility testing

The number of eggs remaining in the ovaries, estimated indirectly through tests.

Ovarian stimulation
IVF treatment

Using fertility medicines to encourage the ovaries to develop multiple mature eggs for IVF.

Ovarian tissue cryopreservation (OTC)
Fertility preservation

Surgically removing and freezing ovarian tissue as a fertility preservation option in select cases.

Ovarian torsion
IVF treatment

A twisting of the ovary that cuts off its blood supply, causing sudden severe pelvic pain and needing urgent care.

Ovarian transposition
Fertility preservation

Surgery to move the ovaries out of a planned radiotherapy field to help protect them.

Ovarian volume
Fertility testing

The measured size of an ovary on ultrasound, used alongside other reserve markers.

Ovulation
Fertility basics

The release of a mature egg from the ovary, usually mid-cycle.

Ovulation induction
IUI & ovulation treatment

Using medicines to stimulate the ovary to release one or more mature eggs.

P

Painful intercourse
Lifestyle & preconception

Pain during sex has recognised causes and can affect the chance of natural conception; it is worth investigating.

Parentage of a child born through surrogacy
Surrogacy

Legal parentage of a surrogacy-born child rests with the commissioning couple under the Surrogacy Act.

Pathogenic variant and variant of uncertain significance (VUS)
Genetics & PGT

A gene change known to cause disease, versus one whose effect is not yet clear.

Patient rights and complaints under the ART framework
India ART regulation

Patients have rights to informed consent, confidentiality and registered care, with a route to complain if these are not met.

Pelvic abscess
IVF treatment

A collection of infected fluid in the pelvis, a rare but serious complication that needs urgent treatment.

Pelvic adhesions
Female fertility

Bands of internal scar tissue that stick pelvic organs together and can affect fertility.

Pelvic infection after egg retrieval
IVF treatment

An uncommon infection of the pelvic organs that can follow egg retrieval, needing prompt clinic assessment.

Pelvic inflammatory disease (PID)
Infections

An infection of the upper genital tract — uterus, tubes and ovaries — that can damage fertility.

Pelvic ultrasound
Fertility testing

An ultrasound scan of the uterus, ovaries and pelvis, done abdominally or vaginally.

Peritoneal adhesions
Female fertility

Scar tissue involving the peritoneum, the lining of the abdominal and pelvic cavity.

PGT fee
Costs & access

The additional charge for genetic testing of embryos, billed per embryo tested.

PGT-A (preimplantation genetic testing for aneuploidy)
Genetics & PGT

Testing embryos for the correct number of chromosomes before transfer.

PGT-M (preimplantation genetic testing for monogenic disorders)
Genetics & PGT

Embryo testing for a specific single-gene condition already known in the family.

PGT-SR (preimplantation genetic testing for structural rearrangements)
Genetics & PGT

Embryo testing when a parent carries a balanced chromosome rearrangement.

Pituitary adenoma
Anatomy & hormones

A usually benign growth of the pituitary gland that can disrupt hormone levels controlling ovulation.

Polycystic ovarian morphology (PCOM)
Female fertility

An ultrasound appearance of many small follicles, one feature used to diagnose PCOS.

Polycystic ovary syndrome (PCOS)
Female fertility

A common hormonal condition causing irregular ovulation, and often excess androgens and polycystic-appearing ovaries.

Poor ovarian response (POR)
IVF treatment

Fewer eggs and follicles than expected growing during ovarian stimulation for IVF.

Post-wash sperm count
IUI & ovulation treatment

The concentration and motility of sperm remaining after laboratory washing, used to judge IUI suitability.

Preconception care
Lifestyle & preconception

Health checks and lifestyle steps taken before trying to conceive, to support a healthy pregnancy.

Pregnancy of unknown location (PUL)
Pregnancy loss

A positive pregnancy test where no pregnancy has yet been seen on scan, in or outside the uterus.

Preimplantation genetic testing (PGT)
Genetics & PGT

Laboratory testing of cells from an embryo before transfer, alongside IVF.

Premature ovarian insufficiency (POI)
Female fertility

Loss of normal ovarian function before the age of 40.

Premature ovulation
IVF treatment

When ovulation occurs earlier than planned during a stimulated IVF or IUI cycle, before eggs can be collected.

Primary infertility
Fertility basics

Infertility in a couple who have never had a pregnancy.

Products of conception
Pregnancy loss

Pregnancy tissue passed or removed after a miscarriage, which can sometimes be tested for a genetic cause.

Progesterone
Anatomy & hormones

The hormone that prepares and supports the uterine lining after ovulation.

Progesterone for luteal support
Fertility medicines

Progesterone medicine given after embryo transfer to support the uterine lining for possible implantation.

Progestin-primed ovarian stimulation
IVF treatment

An IVF stimulation protocol using a progestin medicine to prevent premature ovulation.

Programmed FET
IVF treatment

Preparing the endometrium for frozen embryo transfer with hormone medicines rather than relying on natural ovulation.

Prohibited practices under the ART Act
India ART regulation

Practices the ART (Regulation) Act, 2021 specifically bans, such as sex selection and unregistered treatment.

Prolactin
Anatomy & hormones

A pituitary hormone that, when raised, can suppress ovulation.

Prolactinoma
Anatomy & hormones

A benign pituitary tumour that secretes excess prolactin, commonly causing irregular periods or absent ovulation.

Pronuclei (PN) and normal or abnormal fertilisation
Embryology

Two visible structures seen the morning after IVF that confirm normal fertilisation; other counts need a closer look.

Proximal tubal obstruction
Female fertility

Blockage at the end of the tube nearest the uterus.

Pyosalpinx
Infections

A fallopian tube filled with pus, usually during an active pelvic infection.

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Random-start stimulation
Fertility preservation

Starting ovarian stimulation for egg freezing at any point in the menstrual cycle, not only at its start.

Record keeping and confidentiality under the ART Act
India ART regulation

Legal duties on ART clinics and banks to keep accurate records and protect patient and donor confidentiality.

Recurrent implantation failure (RIF)
IVF treatment

Repeated failure of good-quality embryos to implant after transfer, a term without a single agreed definition.

Recurrent pregnancy loss (RPL)
Pregnancy loss

The loss of two or more pregnancies, prompting investigation into possible underlying causes.

Registered ART clinic and checking registration
India ART regulation

Only clinics listed on the National ART & Surrogacy Registry may lawfully offer ART treatment in India.

Registered surrogacy clinic
Surrogacy

A facility permitted to carry out surrogacy procedures, registered under the Surrogacy Act.

Registration, renewal, suspension and cancellation
India ART regulation

The process by which an ART clinic or bank's legal status to operate is granted, renewed, suspended or withdrawn.

Reproductive age
Fertility basics

The life stage during which natural pregnancy is biologically possible.

Reproductive tract infection (RTI)
Infections

An infection of the genital tract, which may or may not be sexually transmitted.

Rescue ICSI
Embryology

Injecting sperm into eggs that show no sign of fertilisation after conventional IVF, on the same day.

Retained products of conception
Pregnancy loss

Pregnancy tissue that remains in the uterus after a miscarriage or delivery and may need further treatment.

Retrograde ejaculation
Male fertility

Semen passes backward into the bladder at orgasm instead of leaving the body.

Rotterdam criteria
Female fertility

The widely used diagnostic checklist for PCOS, requiring two of three features to be present.

Round cells in semen
Fertility testing

Non-sperm cells seen in semen that may be white blood cells or immature sperm-forming cells.

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Saline infusion sonography (SIS)
Fertility testing

An ultrasound scan with fluid instilled into the uterus to check the uterine cavity.

Salpingectomy
Female fertility

Surgical removal of a fallopian tube, often for hydrosalpinx before IVF.

Salpingitis
Infections

Inflammation of the fallopian tube, usually caused by an ascending infection.

Salpingostomy
Female fertility

Surgery to open a blocked fallopian tube to try to restore its function.

Secondary infertility
Fertility basics

Difficulty conceiving again after a previous pregnancy.

Self-pay and financing
Costs & access

Paying for fertility treatment directly, including loans or instalment plans offered by some clinics.

Semen analysis
Fertility testing

The basic laboratory test that assesses semen volume, sperm count, motility and shape.

Semen sample and collection
Fertility testing

How a semen sample is produced and handled for accurate testing.

Semen volume
Male fertility

The total amount of fluid produced in one ejaculate.

Severe oligozoospermia
Male fertility

A markedly low sperm concentration, well below the standard reference range.

Sex selection and sex determination
India ART regulation

Both are prohibited in India: choosing a child's sex, and revealing or trying to learn it before or during pregnancy.

Sexual health terms in fertility care
Lifestyle & preconception

Erectile, ejaculatory and libido difficulties are common, treatable, and worth discussing openly in fertility care.

Sexually transmitted infection (STI)
Infections

An infection passed between partners through sexual contact, some of which can affect fertility.

Sharps container and safe disposal
Fertility medicines

A puncture-proof container used to safely collect and dispose of used needles and syringes.

Sickle-cell disease
Genetics & PGT

An inherited blood disorder causing red blood cells to become sickle-shaped.

Single embryo transfer (SET)
IVF treatment

Transferring one embryo in a cycle, the main way to reduce the chance of a multiple pregnancy.

Smoking and tobacco
Lifestyle & preconception

Smoking and smokeless tobacco use are linked to reduced fertility in both women and men.

Sperm agglutination
Male fertility

Motile sperm sticking together in clumps, noted during semen analysis.

Sperm concentration
Male fertility

The number of sperm present in each millilitre of semen.

Sperm DNA fragmentation
Fertility testing

A measure of breaks or damage in the genetic material carried inside sperm.

Sperm freezing (sperm cryopreservation)
Fertility preservation

Freezing a semen sample so it can be used for future fertility treatment.

Sperm morphology
Male fertility

The shape and structure of sperm, assessed as part of a semen analysis.

Sperm motility
Male fertility

How sperm move, graded as progressive, non-progressive or immotile.

Sperm vitality
Male fertility

The proportion of sperm in a sample that are alive, distinct from whether they are moving.

Sperm washing
IUI & ovulation treatment

Laboratory processing of a semen sample to separate healthy motile sperm for IUI or IVF.

Spinal muscular atrophy (SMA)
Genetics & PGT

An inherited condition causing progressive muscle weakness, screened for as a carrier condition.

Split IVF/ICSI
Embryology

Dividing eggs from one cycle between conventional IVF and ICSI.

Sterility
Fertility basics

A clinical term for an absolute, irreversible inability to conceive.

Stimulated IUI
IUI & ovulation treatment

IUI combined with ovulation-inducing medicines to encourage one or two follicles to mature.

Stimulation protocol
IVF treatment

The overall medicine plan used to control ovarian stimulation during IVF, chosen by the treating team.

Storing fertility medicines in Indian conditions
Fertility medicines

Guidance on keeping fertility medicines safe during heat, power cuts and travel, following the label and pharmacist.

Subchorionic haematoma
Pregnancy after treatment

A small pool of blood between the gestational sac and the uterine wall, sometimes seen on early scans.

Subclinical hypothyroidism
Fertility testing

A mildly raised TSH with normal thyroid hormone levels, sometimes treated in fertility care.

Subcutaneous injection
Fertility medicines

A method of giving medicine as a shallow injection into the fatty layer just under the skin.

Subfertility
Fertility basics

Reduced likelihood of natural conception, without ruling it out.

Submucosal fibroid
Female fertility

A fibroid that bulges into the uterine cavity, the type most likely to affect fertility and implantation.

Subserosal fibroid
Female fertility

A fibroid on the outer surface of the uterus, generally with the least impact on fertility.

Support after pregnancy loss in India
Pregnancy loss

Sources of medical, practical and emotional support available in India after a pregnancy loss.

Surgical sperm retrieval
Male fertility

Procedures to collect sperm directly from the epididymis or testis for use with ICSI.

Surrogacy
Surrogacy

An arrangement where a woman carries a pregnancy for another person or couple, regulated in India by the Surrogacy Act.

Surrogacy (Regulation) Act, 2021
Surrogacy

India's law permitting only altruistic gestational surrogacy under registered surrogacy clinics.

Surrogacy Rules and later amendments
Surrogacy

The detailed operational rules under the Surrogacy Act, updated by amendments including changes in 2024.

Surrogate insurance cover
Surrogacy

Mandatory insurance protecting a surrogate's health during and after the surrogacy pregnancy.

Surrogate mother
Surrogacy

A woman who carries a pregnancy for a commissioning couple under the conditions set by the Surrogacy Act.

Syphilis
Infections

A bacterial STI that is screened for before fertility treatment and can affect pregnancy if untreated.

T

TB PCR in fertility testing
Fertility testing

A molecular test for tuberculosis DNA, used cautiously in evaluating suspected genital TB.

Telling a child about donor conception
Donor conception

Deciding how, whether and when to explain donor conception to a donor-conceived child.

Teratozoospermia
Male fertility

A lower than expected proportion of sperm with a typical shape on semen analysis.

Testicular torsion
Anatomy & hormones

A medical emergency where the testis twists on its blood supply, needing urgent treatment.

Testosterone (and free testosterone/SHBG)
Anatomy & hormones

The main male sex hormone, essential for sperm production.

Thin endometrium
IVF treatment

A uterine lining thinner than typically expected around ovulation or embryo transfer, which can lower implantation chances.

Third-party reproduction
Donor conception

An umbrella term for fertility treatment involving a donor or surrogate outside the intending parents.

Threatened miscarriage
Pregnancy loss

Bleeding in early pregnancy while the pregnancy is still confirmed to be developing on scan.

Thrombophilia
Pregnancy loss

A tendency towards abnormal blood clotting, sometimes tested for after recurrent pregnancy loss but not needed by everyone.

Thyroid peroxidase antibody (TPO antibody)
Fertility testing

An antibody test used to detect autoimmune thyroid disease.

Thyroid-stimulating hormone (TSH)
Fertility testing

The pituitary hormone used to screen for thyroid problems affecting fertility.

Time-lapse imaging and other laboratory add-ons
IVF treatment

Extra IVF laboratory techniques, such as continuous embryo monitoring, offered at added cost with uncertain overall benefit.

Timed intercourse
IUI & ovulation treatment

Planning intercourse around the fertile window, sometimes alongside ovulation-inducing medicines.

Total motile sperm count (TMSC)
Male fertility

The number of actively moving sperm in a sample, often used to guide treatment choice.

Total sperm count
Male fertility

The total number of sperm in the full ejaculate, combining concentration and volume.

Transfer catheter and ultrasound-guided transfer
IVF treatment

The thin tube used to pass an embryo into the uterus, usually guided by abdominal ultrasound; sometimes tested beforehand.

Transfer of gametes or embryos between facilities
India ART regulation

Movement of gametes or embryos between registered ART clinics or banks must follow documented, lawful procedures.

Translocation
Genetics & PGT

A rearrangement where chromosome material is swapped or moved between chromosomes.

Transvaginal ultrasound (TVS)
Fertility testing

An internal ultrasound scan giving a detailed view of the uterus and ovaries.

Treatment package
Costs & access

A bundled clinic quote for a course of fertility treatment; check exactly what it includes.

Trigger injection
IVF treatment

A medicine given at a precise time in IVF or IUI to complete final egg maturation before retrieval or ovulation.

Tubal blockage
Female fertility

A fallopian tube that is closed off, stopping the egg and sperm from meeting normally.

Tubal cannulation
Female fertility

A procedure to clear a blockage at the point where a fallopian tube meets the uterus.

Tubal patency
Fertility testing

Whether a fallopian tube is open and able to let an egg and sperm pass through.

Tubal tuberculosis
Infections

Genital tuberculosis affecting the fallopian tubes, the most common site of female genital TB.

Tubo-ovarian abscess
Infections

A pocket of infected pus involving both the tube and ovary, a serious complication of pelvic infection.

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