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Fertility Glossary

Liquefaction

The normal process by which freshly ejaculated semen changes from a gel to a liquid.

Male fertility

Semen is usually thick or gel-like immediately after ejaculation and normally liquefies into a more fluid consistency within around 15 to 60 minutes, an effect of enzymes from the prostate. Laboratories note the time taken to liquefy as part of a semen analysis. Delayed or incomplete liquefaction can make it harder to assess sperm motility and concentration accurately and may relate to prostate or seminal vesicle function; the laboratory can use additional processing steps when this happens, and a repeat test is often useful.

Also known as: delayed liquefaction

Sources

  • World Health Organization (who.int)

Last reviewed: 9 September 2026. Written by the Antega Editorial Team. General information only โ€” always follow the advice of your own clinic, doctor or pharmacist.

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