Intrauterine insemination (IUI)

Intrauterine insemination (IUI) is a fertility treatment in which a prepared sperm sample is placed directly into the uterine cavity using a thin catheter, timed to coincide with ovulation. It is used for mild male-factor infertility, unexplained infertility, ovulatory disorders, or when donor sperm is needed, and is usually tried before moving to IVF. IUI may be done in a natural cycle or combined with ovulation-inducing medicines to encourage development of one or two mature follicles. A trigger injection or the natural LH surge determines the timing of the procedure. IUI is less invasive and generally less costly than IVF, but has a lower success rate per cycle, and clinics in India tailor the number of cycles offered based on individual factors and current standards from bodies such as ICMR and FOGSI. IUI does not involve fertilisation outside the body, so it cannot be combined with genetic testing of embryos. Couples who do not conceive after several IUI attempts are usually advised to review other options with their treating specialist.

Also known as: IUI, artificial insemination

Last reviewed: 9 September 2026. Written by the Antega Editorial Team. General information only — always follow the advice of your own clinic, doctor or pharmacist.