Letrozole is an aromatase-inhibitor medicine that is widely used for ovulation induction in women with irregular or absent ovulation, including PCOS, and is often used as a first-line option ahead of clomiphene citrate in current Indian and international practice. It works by temporarily lowering oestrogen levels, which prompts the body to increase FSH and stimulate follicle development. Letrozole use for ovulation induction is considered off-label in many settings, as its original approved use is in breast cancer treatment, and it should only be used under the supervision of a fertility specialist who monitors the ovarian response with ultrasound. This entry does not describe a dose or treatment schedule; these are decided individually by the treating clinician in line with current guidance.
Also known as: letrozole for ovulation induction
Related India guides
Sources
- ICMR Standard Treatment Workflows (icmr.gov.in/standard-treatment-workflows-stws)
- Federation of Obstetric and Gynaecological Societies of India (fogsi.org)
Last reviewed: 9 September 2026. Written by the Antega Editorial Team. General information only — always follow the advice of your own clinic, doctor or pharmacist.