Male-factor infertility

Male-factor infertility means that semen quality or a condition of the male reproductive tract is contributing to difficulty conceiving. It is found in a substantial proportion of couples having fertility investigations, either alone or alongside a female-factor cause, so both partners are usually assessed together. Evaluation typically starts with a detailed history, examination and semen analysis, with further tests such as hormone levels or scans added if the semen analysis is abnormal or the history suggests a specific cause. A semen result outside the reference range does not mean someone cannot father a child; it guides which further tests or treatments may help.

Also known as: male infertility, sperm problem, male factor

Last reviewed: 9 September 2026. Written by the Antega Editorial Team. General information only — always follow the advice of your own clinic, doctor or pharmacist.