Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a condition present from birth in which the uterus and upper part of the vagina do not develop normally, while the ovaries and external genitalia are usually typical. It is usually identified around puberty when periods do not start despite normal breast and pubic hair development. Because the ovaries generally function normally, people with MRKH syndrome can often have genetically related children using their own eggs through IVF combined with a gestational surrogate, where legally permitted, or through other family-building options discussed with a specialist team; surrogacy in India is subject to specific legal eligibility conditions under the Surrogacy (Regulation) Act, 2021.
Also known as: Mayer-Rokitansky-Küster-Hauser syndrome, vaginal agenesis with absent uterus
Sources
- ICMR Standard Treatment Workflows (icmr.gov.in/standard-treatment-workflows-stws)
- Federation of Obstetric and Gynaecological Societies of India (fogsi.org)
Last reviewed: 9 September 2026. Written by the Antega Editorial Team. General information only — always follow the advice of your own clinic, doctor or pharmacist.