Round cells in semen are cells other than mature sperm that appear during microscopic examination, and they can be either white blood cells (leukocytes) or immature germ cells from sperm production. Because the two look similar under a standard microscope, laboratories often use a special stain to tell them apart when the round cell count is raised. Distinguishing the type matters: a high number of white blood cells points toward possible inflammation or infection (leukocytospermia), while a high number of immature germ cells more often reflects a step in sperm production and does not necessarily indicate infection.
Also known as: round cell count, germ cells in semen
Sources
- World Health Organization (who.int)
Last reviewed: 9 September 2026. Written by the Antega Editorial Team. General information only — always follow the advice of your own clinic, doctor or pharmacist.