Sperm agglutination is when motile sperm are seen sticking to each other, head-to-head, tail-to-tail or in mixed patterns, under the microscope during semen analysis. It is different from sperm simply clumping with mucus or cells, which is described separately. Agglutination can sometimes be associated with antisperm antibodies or infection, and may reduce the number of sperm able to move freely toward an egg. Its significance depends on how extensive it is and the rest of the semen picture; further tests such as antisperm antibody testing may be suggested, and treatment options range from no specific action to sperm washing techniques or ICSI depending on severity.
Also known as: sperm clumping, agglutinated sperm
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Sources
- World Health Organization (who.int)
Last reviewed: 9 September 2026. Written by the Antega Editorial Team. General information only — always follow the advice of your own clinic, doctor or pharmacist.