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Fertility Glossary

Agonist trigger

Using a GnRH agonist instead of hCG to mature eggs.

Treatment

An agonist trigger causes the body's own short LH surge and clears from the system quickly, substantially reducing the risk of severe OHSS. Because it also weakens the luteal phase, it is usually combined with a freeze-all approach or with modified luteal support.

Also known as: lupron trigger, buserelin trigger

Sources

  • Royal Australian and New Zealand College of Obstetricians and Gynaecologists (ranzcog.edu.au)
  • European Society of Human Reproduction and Embryology (eshre.eu)

Last reviewed: 10 September 2026. Written by the Antega Editorial Team. General information only โ€” always follow the advice of your own clinic, doctor or pharmacist.

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