Treatment
Down-regulation uses a GnRH agonist to suppress the pituitary so the cycle can be controlled entirely by prescribed medicines. Temporary menopause-like side effects such as hot flushes and headaches are common while it takes effect, and settle once stimulation begins.
Also known as: downreg, pituitary suppression
Sources
- Royal Australian and New Zealand College of Obstetricians and Gynaecologists (ranzcog.edu.au)
Last reviewed: 10 September 2026. Written by the Antega Editorial Team. General information only — always follow the advice of your own clinic, doctor or pharmacist.