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Fertility Glossary

SHBG

A protein that binds sex hormones in the blood.

Hormones

Sex hormone-binding globulin carries testosterone and oestrogen in the bloodstream, controlling how much is freely active. Low SHBG, often seen with insulin resistance, raises free testosterone and is one reason androgen symptoms can appear in PCOS even when total testosterone looks normal.

Also known as: sex hormone binding globulin

Sources

  • Royal College of Pathologists of Australasia (rcpa.edu.au)

Last reviewed: 10 September 2026. Written by the Antega Editorial Team. General information only โ€” always follow the advice of your own clinic, doctor or pharmacist.

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