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Fertility Glossary

CFTR variants and CBAVD

Absent vas deferens linked with cystic fibrosis gene variants.

Genetics

Congenital bilateral absence of the vas deferens causes obstructive azoospermia and is strongly associated with CFTR variants. Sperm can usually be retrieved surgically, and partner CFTR carrier testing is essential before treatment because of the risk of cystic fibrosis in a child.

Also known as: CBAVD, absent vas deferens, cystic fibrosis carrier male

Sources

  • Canadian Urological Association
  • Society of Obstetricians and Gynaecologists of Canada (SOGC) patient information

Last reviewed: September 9, 2026. Written by the Antega Editorial Team. General information only โ€” always follow the advice of your own clinic, doctor or pharmacist.

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