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A–Z Fertility Glossary

325 fertility terms explained in plain language.

325 terms

A

Abnormal fertilisation
Eggs, sperm & embryos

Fertilisation with the wrong number of pronuclei.

Abstinence period
Male fertility

The time since last ejaculation before a semen sample.

Add-ons
IVF & IUI

Optional extras offered alongside IVF, most with limited evidence.

Adenomyosis
Female fertility

Endometrial tissue within the muscular wall of the uterus.

Age and fertility
Fertility basics

Egg number and egg quality decline with age, gradually then faster after the mid-thirties.

Agonist trigger
Medicines & protocols

A GnRH agonist used instead of hCG to mature eggs and cut OHSS risk.

Alcohol and caffeine
Pregnancy after treatment

No known safe level of alcohol in pregnancy; caffeine is usually limited.

Amenorrhoea
Fertility basics

Absence of periods.

AMH (anti-Müllerian hormone)
Tests & investigations

A blood test that estimates the size of the remaining egg pool.

Amniocentesis
Genetics

A diagnostic test sampling amniotic fluid in pregnancy.

Androgens
Hormones

Hormones such as testosterone that are raised in some cases of PCOS.

Anejaculation
Male fertility

Inability to ejaculate.

Aneuploidy
Genetics

An abnormal number of chromosomes in an egg, sperm or embryo.

Anovulation
Fertility basics

Cycles in which no egg is released.

Antagonist protocol
Medicines & protocols

The most common IVF protocol, using a GnRH antagonist to prevent early ovulation.

Anti-Müllerian hormone testing timing
Tests & investigations

AMH can be measured at any point in the cycle.

Antiphospholipid syndrome
Pregnancy after treatment

An autoimmune clotting disorder linked with recurrent loss.

Antisperm antibodies
Male fertility

Immune antibodies that bind sperm and impair movement.

Antral follicle count
Tests & investigations

An ultrasound count of small follicles visible at the start of a cycle.

Asherman syndrome
Female fertility

Scar tissue inside the uterus, usually after surgery or infection.

Assisted hatching
IVF & IUI

Thinning or opening the embryo's outer shell before transfer.

Assisted Human Reproduction Act
Canadian law & regulation

The federal legislation governing assisted reproduction in Canada.

Assisted oocyte activation
Eggs, sperm & embryos

A laboratory technique used after repeated fertilisation failure.

Asthenozoospermia
Male fertility

Reduced sperm motility.

Autoimmune disease and fertility
Pregnancy after treatment

Conditions such as lupus, rheumatoid arthritis and IBD need pre-pregnancy planning.

Azoospermia
Male fertility

No sperm found in the ejaculate.

B

C

Cabergoline
Medicines & protocols

A dopamine agonist used for high prolactin and sometimes for OHSS prevention.

Cancelled cycle
IVF & IUI

A treatment cycle stopped before retrieval or transfer.

Cannabis and fertility
Pregnancy after treatment

Legal in Canada, but not established as safe when trying to conceive or pregnant.

Carrier screening
Genetics

Testing prospective parents for recessive genetic conditions.

CARTR
Clinics, laboratory & costs

The national registry collecting Canadian assisted reproduction cycle data.

Cervical factors
Female fertility

Problems at the cervix that hinder sperm passage or transfer.

Cervical mucus
Fertility basics

Fluid produced by the cervix that becomes stretchy and clear around ovulation.

CFAS
Clinics, laboratory & costs

The Canadian Fertility and Andrology Society, the national professional body.

CFTR variants and CBAVD
Genetics

Absent vas deferens linked with cystic fibrosis gene variants.

Choosing a fertility clinic
Clinics, laboratory & costs

Comparing clinics on outcomes, practice, access and cost.

Chorionic villus sampling
Genetics

A placental sample for genetic diagnosis, usually at 11 to 14 weeks.

Chronic endometritis
Female fertility

Persistent low-grade inflammation of the uterine lining.

Cleavage-stage embryo
Eggs, sperm & embryos

An embryo two or three days after fertilisation, of two to eight cells.

Clinic accreditation
Clinics, laboratory & costs

External assessment of clinic and laboratory standards.

Clomiphene citrate
Medicines & protocols

An older oral medication for ovulation induction.

Compassionate and patient support programmes
Medicines & protocols

Manufacturer programmes that may reduce fertility medication costs.

Conception
Fertility basics

Fertilisation of an egg by a sperm, leading to an embryo.

Congenital uterine anomaly
Female fertility

A uterus formed differently before birth.

Controlled ovarian stimulation
IVF & IUI

Injectable hormones used in IVF to grow several follicles at once.

Corpus luteum
Fertility basics

The structure left behind after ovulation that makes progesterone.

Cross-border treatment
Canadian healthcare & funding

Travelling outside Canada for fertility care.

Cryostorage
Eggs, sperm & embryos

Long-term storage of eggs, sperm or embryos in liquid nitrogen.

Cumulative live birth rate
Clinics, laboratory & costs

The chance of a baby across all transfers from one egg retrieval.

D

Day 3 bloodwork
Tests & investigations

Early-cycle hormone tests, usually FSH, LH and oestradiol.

Diabetes and fertility
Pregnancy after treatment

Blood glucose control before conception affects both fertility and pregnancy.

Difficult transfer
IVF & IUI

A transfer complicated by the shape or narrowness of the cervical canal.

Diminished ovarian reserve
Tests & investigations

Fewer eggs remaining than expected for your age.

Disclosure
Donor treatment & family building

Telling a child about their donor-conceived origins.

Donor anonymity and identity
Donor treatment & family building

Canada has no national donor registry; identity practices vary by source.

Donor conception
Donor treatment & family building

Building a family using donated sperm, eggs or embryos.

Donor eggs
Donor treatment & family building

Eggs donated by another person, used with IVF.

Donor embryos
Donor treatment & family building

Embryos donated by another family after their own treatment.

Donor reimbursement
Canadian law & regulation

Repaying a donor's receipted expenses — the only payment permitted in Canada.

Donor screening
Donor treatment & family building

Health, infection and genetic checks required before donation.

Donor sperm
Donor treatment & family building

Sperm donated by another person, used for IUI or IVF.

Donor-conceived person
Donor treatment & family building

Someone conceived using donated sperm, eggs or embryos.

Drug plan coverage
Canadian healthcare & funding

Whether fertility medications are paid by a public or private drug plan.

E

Ectopic pregnancy
Pregnancy after treatment

A pregnancy implanting outside the uterus, usually in a fallopian tube.

Egg freezing
Eggs, sperm & embryos

Collecting and vitrifying unfertilised eggs for later use.

Egg retrieval
IVF & IUI

The procedure that collects eggs from the ovaries with an ultrasound-guided needle.

Elective single embryo transfer
IVF & IUI

Choosing to transfer one embryo when more are available.

Embryo arrest
Eggs, sperm & embryos

Embryos stopping development before reaching the blastocyst stage.

Embryo biopsy
Genetics

Removing a few cells from a blastocyst for genetic testing.

Embryo disposition
Canadian law & regulation

Deciding what happens to embryos you will not use.

Embryo grade
Eggs, sperm & embryos

A score describing how an embryo looks under the microscope.

Embryo transfer
IVF & IUI

Placing an embryo into the uterus through a fine catheter.

Embryologist
Fertility basics

The laboratory scientist who handles eggs, sperm and embryos.

Embryology laboratory
Clinics, laboratory & costs

The controlled environment where eggs, sperm and embryos are handled.

Embryos after relationship breakdown
Canadian law & regulation

Both people's consent is normally needed to use stored embryos.

Employer fertility benefits
Canadian healthcare & funding

Workplace support ranging from insured coverage to leave arrangements.

Employment leave and appointments
Canadian healthcare & funding

Time off for treatment, and rights around pregnancy loss.

Empty follicle syndrome
IVF & IUI

No eggs recovered despite follicles appearing on scan.

Endometrial biopsy
Tests & investigations

A small sample of the uterine lining taken for laboratory examination.

Endometrial polyp
Female fertility

A small benign growth of the uterine lining.

Endometrioma
Female fertility

An ovarian cyst filled with old blood, caused by endometriosis.

Endometriosis
Female fertility

Endometrial-like tissue growing outside the uterus.

Endometrium
Fertility basics

The lining of the uterus, which thickens each cycle and is shed as a period.

Epilepsy and fertility
Pregnancy after treatment

Seizure control and medication choice both matter before pregnancy.

Erectile dysfunction
Male fertility

Difficulty obtaining or maintaining an erection.

Euploid
Genetics

An embryo with the expected number of chromosomes.

Exercise during treatment
Pregnancy after treatment

Moderate activity is encouraged; high-impact exercise is limited around retrieval.

F

Fecundability
Fertility basics

The chance of conceiving in a single menstrual cycle.

Fertile window
Fertility basics

The roughly six days ending on the day of ovulation when sex can lead to pregnancy.

Fertilisation
Fertility basics

A sperm entering an egg and the two sets of chromosomes combining.

Fertilisation failure
Eggs, sperm & embryos

No eggs fertilising after insemination or ICSI.

Fertility counsellor
Fertility basics

A counsellor with specific training in fertility, donor conception and surrogacy.

Fertility lawyer
Canadian law & regulation

A lawyer specialising in reproductive law and parentage.

Fertility preservation
Eggs, sperm & embryos

Storing eggs, sperm, embryos or tissue to protect future options.

Fertility with one ovary
Female fertility

Conception is usually still possible with a single ovary.

Fertility with one testicle
Male fertility

One healthy testis is often enough for normal sperm production.

First ultrasound after treatment
Pregnancy after treatment

The scan around six to seven weeks that checks the pregnancy's location and heartbeat.

Folic acid
Medicines & protocols

A supplement taken before conception to reduce neural tube defects.

Follicle
Eggs, sperm & embryos

The fluid-filled sac in the ovary that contains a developing egg.

Follicle tracking
Tests & investigations

Serial ultrasound scans that measure growing follicles during a cycle.

Follicular phase
Fertility basics

The first half of the cycle, when follicles grow and the lining rebuilds.

Fragile X premutation
Genetics

A repeat expansion linked with early ovarian insufficiency and fragile X in children.

Fragmentation
Eggs, sperm & embryos

Small cellular fragments seen between the cells of an embryo.

Freeze-all cycle
IVF & IUI

Freezing every suitable embryo instead of transferring in the fresh cycle.

Fresh embryo transfer
IVF & IUI

Transfer during the same cycle as egg retrieval.

Frozen embryo transfer (FET)
IVF & IUI

Transfer of a thawed embryo in a later cycle.

FSH (follicle-stimulating hormone)
Hormones

The pituitary hormone that drives follicles to grow.

Functional hypothalamic amenorrhoea
Female fertility

Periods stopping because of low energy availability, exercise or stress.

G

H

hCG (human chorionic gonadotropin)
Hormones

The pregnancy hormone, also used as a trigger injection.

Health Canada's role in fertility care
Canadian law & regulation

Federal regulator for assisted reproduction, donor safety and medicines.

Health card
Canadian healthcare & funding

Your provincial or territorial health insurance card.

Health spending account
Canadian healthcare & funding

An employer-funded account that can pay eligible medical costs.

Heat exposure and sperm
Male fertility

Sustained scrotal heat can temporarily lower sperm quality.

hMG
Medicines & protocols

Human menopausal gonadotropin, containing both FSH and LH activity.

Hormonal suppression before treatment
Medicines & protocols

Using contraceptives or agonists to plan and prepare a cycle.

HyCoSy / sonohysterosalpingography
Tests & investigations

An ultrasound-based test of tubal patency using contrast rather than X-ray.

Hydrosalpinx
Female fertility

A blocked, fluid-filled fallopian tube.

Hypertension and fertility treatment
Pregnancy after treatment

High blood pressure should be controlled and medications reviewed before pregnancy.

Hyperthyroidism
Hormones

An overactive thyroid, which can also affect cycles and pregnancy.

Hypogonadism
Hormones

Low sex hormone production by the ovaries or testes.

Hypogonadotropic hypogonadism
Hormones

Low sex hormones because the brain is not sending enough FSH and LH.

Hypothalamic–pituitary–ovarian axis
Hormones

The hormone loop between the brain and the ovaries that runs the cycle.

Hypothyroidism
Hormones

An underactive thyroid, which can disturb cycles and pregnancy.

Hysterosalpingography (HSG)
Tests & investigations

An X-ray dye test that shows whether the fallopian tubes are open.

Hysteroscopic myomectomy
Female fertility

Removing a cavity fibroid through the cervix, without abdominal incisions.

Hysteroscopy
Tests & investigations

A camera examination of the inside of the uterus.

I

K

L

M

Mature (MII) oocyte
Eggs, sperm & embryos

An egg that has completed the maturation step needed for fertilisation.

Medical expense tax credit
Canadian healthcare & funding

A federal tax credit that can include certain fertility-related expenses.

Medical records and transfers between clinics
Clinics, laboratory & costs

Moving your history, results and stored material to another clinic.

Medicare (Canada)
Canadian healthcare & funding

Canada's publicly funded health insurance, administered by each province and territory.

Medication review before pregnancy
Medicines & protocols

Checking existing prescriptions for safety in conception and pregnancy.

Medication storage
Medicines & protocols

Keeping fertility medicines at the temperature stated on their Canadian labelling.

Medicines affecting sperm
Medicines & protocols

Some prescribed and non-prescribed products reduce sperm production.

Menopause
Fertility basics

Twelve consecutive months without a period, marking the end of ovulation.

Mental health medicines and conception
Medicines & protocols

Antidepressants and related medicines need a planned, not abrupt, review.

Metformin
Medicines & protocols

An insulin-sensitising medication sometimes used in PCOS.

MicroTESE
Male fertility

Microsurgical testicular sperm extraction under an operating microscope.

Mid-luteal progesterone
Tests & investigations

A blood test about seven days before the expected period that confirms ovulation.

Mild stimulation IVF
Medicines & protocols

IVF using lower medication doses, aiming for fewer eggs.

Miscarriage
Pregnancy after treatment

Loss of a pregnancy before 20 weeks.

Missed miscarriage
Pregnancy after treatment

A pregnancy that has stopped developing before any bleeding starts.

Mitochondrial and germline modification
Canadian law & regulation

Altering the DNA passed to future generations — prohibited in Canada.

Mock embryo transfer
IVF & IUI

A practice run to map the route into the uterus.

Morula
Eggs, sperm & embryos

The compacted ball of cells at around day four.

Mosaic embryo
Genetics

A PGT-A result showing a mixture of normal and abnormal cells.

MRKH syndrome
Female fertility

Being born without a uterus, with normally functioning ovaries.

Multiple pregnancy
Pregnancy after treatment

Twins or more — the main avoidable risk of fertility treatment.

Myomectomy
Female fertility

Surgical removal of fibroids while keeping the uterus.

N

O

Obstructive azoospermia
Male fertility

Sperm are produced but cannot get out.

Oestradiol
Hormones

The main oestrogen, produced by growing follicles.

Oestrogen preparations
Medicines & protocols

Tablets or patches used to build the lining in frozen transfer cycles.

OHSS (ovarian hyperstimulation syndrome)
IVF & IUI

An excessive response to fertility drugs that makes the ovaries swell and fluid shift.

OHSS prevention
IVF & IUI

Steps that reduce the risk of ovarian hyperstimulation syndrome.

Oligo-ovulation
Fertility basics

Ovulating infrequently or unpredictably.

Oligomenorrhoea
Fertility basics

Infrequent periods, typically cycles longer than 35 days.

Oligospermia
Male fertility

A low sperm concentration.

Ontario Fertility Program
Canadian healthcare & funding

Ontario's publicly funded fertility programme, delivered through participating clinics.

Oocyte
Eggs, sperm & embryos

The medical word for an egg.

Orchidopexy
Male fertility

Surgery to bring an undescended testis into the scrotum.

Orchitis and epididymitis
Male fertility

Inflammation or infection of the testis or epididymis.

Ovarian cyst
Female fertility

A fluid-filled sac on the ovary, usually harmless.

Ovarian reserve
Tests & investigations

An estimate of how many eggs remain in the ovaries.

Ovarian tissue freezing
Eggs, sperm & embryos

Surgically removing and freezing ovarian tissue for later re-implantation.

Ovarian torsion
Female fertility

The ovary twisting on its blood supply — a surgical emergency.

Ovulation
Fertility basics

The release of a mature egg from an ovary, usually once per cycle.

Ovulation induction
IVF & IUI

Medication used to make the ovaries release an egg.

Ovulation predictor kit
Tests & investigations

A urine test that detects the LH surge a day or so before ovulation.

P

Peer support and community services
Canadian healthcare & funding

Groups and services offering support alongside clinical care.

Pelvic adhesions
Female fertility

Bands of scar tissue that distort pelvic anatomy.

Pelvic inflammatory disease
Female fertility

Infection of the upper genital tract, often from untreated chlamydia or gonorrhoea.

Pelvic ultrasound
Tests & investigations

A scan of the uterus, ovaries and pelvis.

Perimenopause
Fertility basics

The years of hormonal change leading up to the last period.

PGT-A
Genetics

Testing embryos for the correct number of chromosomes.

PGT-M
Genetics

Testing embryos for a specific inherited single-gene condition.

PGT-SR
Genetics

Testing embryos where a parent carries a chromosome rearrangement.

Pituitary gland
Hormones

The gland at the base of the brain that controls FSH and LH release.

Polar body
Eggs, sperm & embryos

A small cell extruded by the egg as it matures.

Polycystic ovary syndrome (PCOS)
Female fertility

A common hormonal condition causing irregular ovulation.

Poor ovarian response
IVF & IUI

Very few follicles or eggs despite adequate stimulation.

Post-vasectomy semen analysis
Tests & investigations

The test confirming sperm are absent after a vasectomy.

Posthumous use of reproductive material
Canadian law & regulation

Use after death requires specific, prior written consent.

Preconception screening
Tests & investigations

Blood tests and checks offered before pregnancy or treatment.

Pregnancy after loss
Pregnancy after treatment

A pregnancy carried alongside the anxiety of previous loss.

Pregnancy of unknown location
Pregnancy after treatment

A positive pregnancy test with nothing yet visible on ultrasound.

Preimplantation genetic testing (PGT)
Genetics

Testing embryos before transfer for chromosome or gene conditions.

Premature ovarian insufficiency
Female fertility

Ovarian function ending before age 40.

Preterm birth
Pregnancy after treatment

Birth before 37 weeks.

Primary infertility
Fertility basics

Never having conceived before.

Primary-care provider
Fertility basics

Your family physician or nurse practitioner — usually the route into fertility care.

Private insurance and fertility benefits
Canadian healthcare & funding

Employer or personal insurance that may cover fertility drugs or treatment.

Progesterone
Hormones

The hormone that prepares and maintains the uterine lining after ovulation.

Progesterone preparations
Medicines & protocols

Vaginal, oral or injectable forms used to support the luteal phase.

Prohibited activities
Canadian law & regulation

Acts banned outright by Canada's federal assisted reproduction law.

Prolactin
Hormones

The hormone of milk production, which suppresses ovulation when high.

Prolactin test
Tests & investigations

A blood test for the hormone that can suppress ovulation when raised.

Provincial coverage
Canadian healthcare & funding

Fertility funding set by each province or territory, not nationally.

Provincial fertility tax credits and grants
Canadian healthcare & funding

Several provinces offer credits or grants rather than direct funding.

Proximal tubal blockage
Female fertility

A blockage where the tube joins the uterus.

Q

R

S

Saline infusion sonohysterography
Tests & investigations

An ultrasound with saline in the uterus to outline the cavity.

Salpingectomy
Female fertility

Surgical removal of a fallopian tube.

Satellite monitoring
Canadian healthcare & funding

Having scans and bloodwork locally while the main clinic directs the cycle.

Secondary infertility
Fertility basics

Difficulty conceiving after a previous pregnancy.

Sedation for fertility procedures
IVF & IUI

Medication given so egg retrieval is comfortable.

Semen analysis
Male fertility

A laboratory test of sperm volume, concentration, motility and morphology.

Semen culture
Tests & investigations

A laboratory test for infection in semen.

Sex selection
Canadian law & regulation

Choosing an embryo's sex — prohibited in Canada except to avoid a sex-linked disorder.

Sharps disposal
Medicines & protocols

Safe disposal of used fertility injection needles.

SHBG
Hormones

A protein that binds sex hormones and affects how much is active.

Single embryo transfer
IVF & IUI

Transferring one embryo at a time to avoid twin pregnancy.

Slow-rising hCG
Pregnancy after treatment

hCG increasing more slowly than expected in early pregnancy.

Smoking, vaping and fertility
Pregnancy after treatment

Smoking reduces fertility in all genders and raises pregnancy risks.

SOGC
Clinics, laboratory & costs

The Society of Obstetricians and Gynaecologists of Canada.

Solo parenthood by choice
Donor treatment & family building

Choosing to become a parent without a partner, usually with donor gametes.

Specialty pharmacy
Medicines & protocols

Pharmacies that dispense and deliver fertility medications.

Sperm concentration
Male fertility

The number of sperm per millilitre of semen.

Sperm DNA fragmentation testing
Tests & investigations

A test of DNA damage in sperm, with a limited and debated role.

Sperm freezing
Eggs, sperm & embryos

Storing sperm for future treatment.

Sperm morphology
Male fertility

The proportion of sperm with a normal shape.

Sperm motility
Male fertility

The proportion of sperm that are moving, and how well.

Sperm wash / preparation
IVF & IUI

Laboratory processing that concentrates the most motile sperm.

Spermatogenesis
Male fertility

The roughly 72-day process of making sperm.

STI screening
Tests & investigations

Testing for sexually transmitted infections, notably chlamydia and gonorrhoea.

Storage consent
Canadian law & regulation

The written consent that governs stored eggs, sperm and embryos.

Storage fees
Clinics, laboratory & costs

Annual charges for keeping eggs, sperm or embryos frozen.

Subfertility
Fertility basics

Reduced fertility rather than an absolute inability to conceive.

Submucosal fibroid
Female fertility

A fibroid bulging into the uterine cavity.

Surgical sperm retrieval
Male fertility

Collecting sperm directly from the epididymis or testis.

Surrogate (gestational carrier)
Donor treatment & family building

Someone who carries a pregnancy for intended parents.

T

Testicular cancer and fertility
Male fertility

The most common cancer in younger men, with important fertility implications.

Testicular torsion
Male fertility

A twisted testis cutting off its blood supply — an emergency.

Testosterone
Hormones

The main male sex hormone, essential for sperm production.

Testosterone therapy and fertility
Male fertility

Taking testosterone suppresses the body's own sperm production.

Thin endometrium
Female fertility

A uterine lining that stays thinner than expected before transfer.

Third-party reproduction
Donor treatment & family building

Any treatment involving a donor or surrogate.

Thrombophilia
Pregnancy after treatment

An inherited or acquired tendency to clot.

Thyroid antibodies
Tests & investigations

Antibodies indicating autoimmune thyroid disease.

Thyroid function tests
Tests & investigations

Blood tests, chiefly TSH, that check thyroid activity.

Time-lapse imaging
IVF & IUI

Continuous photography of embryos inside a special incubator.

Total motile count
Male fertility

Volume × concentration × motility — the practical measure for choosing treatment.

Transgender fertility preservation
Donor treatment & family building

Storing eggs or sperm before gender-affirming hormone therapy or surgery.

Transition to pregnancy care
Pregnancy after treatment

Moving from the fertility clinic to maternity care.

Transvaginal ultrasound
Tests & investigations

An internal ultrasound giving a clear view of the ovaries and uterus.

Trigger injection
Medicines & protocols

The timed injection that matures the eggs before retrieval.

Trophectoderm
Eggs, sperm & embryos

The outer cell layer of a blastocyst that becomes the placenta.

Tubal patency
Tests & investigations

Whether the fallopian tubes are open along their length.

Tubal surgery
Female fertility

Operations to repair or reopen fallopian tubes.

Turner syndrome
Genetics

A missing or altered X chromosome in females, usually causing ovarian insufficiency.

Two pronuclei (2PN)
Eggs, sperm & embryos

The normal appearance of a fertilised egg the day after insemination.

Two-week wait
IVF & IUI

The interval between transfer or insemination and the pregnancy test.

U

V

W

Y

Z