Recurrent pregnancy loss

Canadian practice investigates after two or three losses, and after one in some circumstances such as later loss or advanced age. Standard investigation includes parental karyotypes where indicated, antiphospholipid antibodies, thyroid function and assessment of the uterine cavity. About half of couples have no cause identified, and most still go on to a successful pregnancy.

Also known as: RPL, repeated miscarriage, recurrent miscarriage

Last reviewed: September 9, 2026. Written by the Antega Editorial Team. General information only — always follow the advice of your own clinic, doctor or pharmacist.