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Fertility Glossary

Two pronuclei (2PN)

The normal appearance of a fertilised egg the day after insemination.

Eggs, sperm & embryos

Seeing two pronuclei — one from the egg, one from the sperm — confirms normal fertilisation. One or three pronuclei indicate abnormal fertilisation, and those zygotes are not used for transfer.

Also known as: 2PN, fertilisation check

Sources

  • Canadian Fertility and Andrology Society (CFAS)

Last reviewed: September 9, 2026. Written by the Antega Editorial Team. General information only — always follow the advice of your own clinic, doctor or pharmacist.

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