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Fertility Glossary

SHBG

A protein that binds sex hormones and affects how much is active.

Hormones

Sex hormone binding globulin carries testosterone and oestradiol in the blood. Low SHBG, common with insulin resistance, increases the fraction of free testosterone and can worsen the symptoms of PCOS.

Also known as: sex hormone binding globulin

Related Canada guides

Sources

  • Society of Obstetricians and Gynaecologists of Canada (SOGC) patient information

Last reviewed: September 9, 2026. Written by the Antega Editorial Team. General information only โ€” always follow the advice of your own clinic, doctor or pharmacist.

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