Add-ons
Assisted oocyte activation exposes injected eggs to a calcium ionophore to trigger the activation step that sometimes fails after ICSI. It is used selectively after total fertilisation failure or very low fertilisation, and is considered experimental in wider use, so it should be discussed as such.
Also known as: AOA, calcium ionophore
Sources
- European Society of Human Reproduction and Embryology (eshre.eu)
Last reviewed: 10 September 2026. Written by the Antega Editorial Team. General information only — always follow the advice of your own clinic, doctor or pharmacist.