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Fertility Glossary

Sperm DNA fragmentation

A test measuring breaks in the genetic material of sperm.

Male fertility

DNA fragmentation testing estimates damage to sperm DNA, which is associated with lower fertilisation and higher miscarriage rates in some studies. It is not part of routine assessment in Australia; results rarely change treatment, and thresholds differ between tests. Discuss cost and what would change before paying for it.

Also known as: DFI, DNA fragmentation index, sperm DNA damage

Related Australia guides

Sources

  • Healthy Male (healthymale.org.au)
  • Royal Australian and New Zealand College of Obstetricians and Gynaecologists (ranzcog.edu.au)

Last reviewed: 10 September 2026. Written by the Antega Editorial Team. General information only โ€” always follow the advice of your own clinic, doctor or pharmacist.

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