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Fertility Glossary

Antiphospholipid syndrome (APS)

An immune condition linked with clotting and recurrent pregnancy loss.

Tests & investigations

Antiphospholipid syndrome is diagnosed when specific antibodies are found on two occasions at least twelve weeks apart, together with a history of clots or particular pregnancy complications. It is one of the few consistently treatable causes of recurrent miscarriage, usually managed in pregnancy with low-dose aspirin and heparin under specialist supervision.

Also known as: APS, Hughes syndrome, antiphospholipid antibodies, lupus anticoagulant

Sources

  • RCOG guidance on recurrent miscarriage
  • ESHRE guidelines and patient information

Last reviewed: 8 September 2026. Written by the Antega Editorial Team. General information only β€” always follow the advice of your own clinic, doctor or pharmacist.

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