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Fertility Glossary

PGT-SR

Testing embryos when a parent carries a chromosome rearrangement.

Genetics

PGT-SR is used when one partner carries a structural rearrangement such as a balanced translocation or inversion. Carriers are usually healthy but can produce eggs or sperm with unbalanced chromosomes, causing failed implantation or miscarriage. Testing identifies embryos with a balanced or normal arrangement for transfer.

Also known as: translocation testing, structural rearrangement testing

Sources

  • ESHRE/ICMART glossary and ESHRE laboratory guidance

Last reviewed: 8 September 2026. Written by the Antega Editorial Team. General information only β€” always follow the advice of your own clinic, doctor or pharmacist.

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