Female fertility
POI causes irregular or absent periods and low oestrogen. Natural pregnancy is still occasionally possible, but many people consider donor eggs. Hormone replacement is usually recommended for long-term health.
Also known as: POI, primary ovarian insufficiency, premature ovarian failure, early menopause
Last reviewed: 23 September 2026. Written by the Antega Editorial Team. General information only — always follow the advice of your own clinic, doctor or pharmacist.