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A–Z Fertility Glossary

406 fertility terms explained in plain language.

406 terms

A

Abnormal fertilisation
Embryology

Fertilisation with an unexpected number of pronuclei, such as one or three.

Additional treatment cost
Costs & clinic terminology

Charges on top of the base price, such as ICSI, freezing or add-ons.

Adenomyosis
Female fertility

Uterine-lining-like tissue growing into the muscular wall of the uterus.

Alcohol and fertility
Lifestyle & preconception

How drinking alcohol may affect conception and pregnancy.

Amenorrhoea
Menstrual cycle & ovulation

Absence of periods.

Andrologist
Male fertility

A specialist in male reproductive health.

Aneuploidy
Genetics & PGT

Having an extra or missing chromosome.

Anovulation
Menstrual cycle & ovulation

The absence of ovulation in a menstrual cycle.

Antagonist Protocol
IVF & treatment

A short IVF stimulation protocol using GnRH antagonists.

Anti-Müllerian hormone (AMH)
Fertility testing

Anti-Müllerian hormone — a blood marker of ovarian reserve.

Antisperm antibodies
Male fertility

Immune proteins that attach to sperm and may reduce their movement.

Antral follicle
IVF & treatment

A small, fluid-filled follicle visible on ultrasound early in the cycle.

Antral follicle count (AFC)
Fertility testing

Antral follicle count — an ultrasound-based estimate of ovarian reserve.

Asherman syndrome
Female fertility

Scar tissue inside the uterus, often after surgery or infection.

Assisted conception
Fertility basics

Any treatment that helps conception happen with medical support.

Assisted Hatching
Treatment add-ons

Laboratory thinning of the embryo's outer shell.

Assisted oocyte activation
Treatment add-ons

Laboratory treatment to trigger egg activation after ICSI.

Assisted reproductive technology (ART)
Fertility basics

Treatments in which eggs or embryos are handled outside the body.

Asthenozoospermia
Male fertility

Lower-than-expected sperm movement.

Azoospermia
Male fertility

No sperm present in the ejaculate.

B

C

Caffeine and fertility
Lifestyle & preconception

Guidance on caffeine when trying to conceive or pregnant.

Cancelled IVF cycle
IVF & treatment

A cycle stopped before egg collection or embryo transfer.

Carrier screening
Genetics & PGT

Testing whether someone carries a gene variant for an inherited condition.

CBAVD
Genetics & PGT

Congenital bilateral absence of the vas deferens.

Cervical Mucus
Menstrual cycle & ovulation

Vaginal secretion produced by the cervix.

Cervix
Anatomy & hormones

The lower, narrow part of the uterus that opens into the vagina.

Cetrorelix
Medicines

A GnRH antagonist that prevents early ovulation.

Chlamydia screening
Fertility testing

Testing for chlamydia before procedures on the uterus or tubes.

Chromosomal Abnormality
Genetics & PGT

An abnormal number or structure of chromosomes.

Chromosome
Genetics & PGT

A package of DNA carrying genes; most cells have 46.

Chronic endometritis
Female fertility

Long-standing, low-grade inflammation of the uterine lining.

Cleavage-stage embryo
Embryology

An embryo in the first days of cell division, before it compacts.

Clinic success rate
Costs & clinic terminology

A clinic's reported chance of pregnancy or birth after treatment.

Clinic-recruited donor
Donor conception

A donor recruited by a clinic or sperm/egg bank rather than known to you.

Clinical pregnancy
Pregnancy after fertility treatment

A pregnancy confirmed on ultrasound, usually by a gestational sac.

Clinical pregnancy rate
Pregnancy after fertility treatment

The proportion of cycles or transfers resulting in a clinical pregnancy.

Clomifene citrate
Medicines

An oral medication to induce ovulation.

Co-parenting
Inclusive family building

Two or more people who are not in a relationship raising a child together.

Compaction
Embryology

When an embryo's cells press tightly together around day 3 to 4.

Conception
Fertility basics

The start of a pregnancy, from fertilisation to implantation.

Congenital uterine abnormality
Female fertility

A difference in uterine shape present from birth.

Consent to storage
UK regulation & HFEA

Written agreement for eggs, sperm or embryos to be frozen and stored.

Consent to treatment
UK regulation & HFEA

Your written agreement to the treatment you will receive.

Consultation fee
Costs & clinic terminology

The charge for appointments with a consultant.

Conventional IVF
IVF & treatment

IVF where sperm and eggs are placed together so fertilisation happens naturally in the dish.

CoQ10
Lifestyle & preconception

Coenzyme Q10 — a supplement studied in egg and sperm quality.

Corpus Luteum
Anatomy & hormones

The structure formed after ovulation that produces progesterone.

Cryopreservation
Fertility preservation

Freezing eggs, sperm or embryos for future use.

Cumulative live birth rate
Pregnancy after fertility treatment

The chance of a live birth from all embryos from one egg collection, fresh and frozen.

Cycle cancellation policy
Costs & clinic terminology

What a clinic charges or refunds if a cycle is stopped.

Cycle day 1
Menstrual cycle & ovulation

The first day of full menstrual bleeding.

D

Day 2 embryo
Embryology

An embryo two days after egg collection, usually with around two to four cells.

Day 3 Embryo
Embryology

A cleavage-stage embryo about 3 days after fertilisation.

DHEA
Treatment add-ons

A hormone sometimes used to support ovarian response.

Diluent
Medicines

The liquid used to dissolve a powdered medicine before injection.

Diminished Ovarian Reserve
Female fertility

Lower-than-expected egg supply for age.

Dominant follicle
Menstrual cycle & ovulation

The follicle that grows largest and releases an egg in a natural cycle.

Donor compensation
Donor conception

The fixed payment UK donors can receive, set by the HFEA.

Donor conception
Donor conception

Having a child using donated eggs, sperm or embryos.

Donor consent
Donor conception

A donor's written consent to how their eggs, sperm or embryos may be used and stored.

Donor Egg
Donor conception

An egg from another woman used in IVF.

Donor family
Inclusive family building

A family created with the help of a donor.

Donor information
Donor conception

Details about a donor that are recorded on the HFEA Register.

Donor insemination (DI)
Donor conception

Insemination using donor sperm.

Donor Sperm
Donor conception

Sperm from a donor used in fertility treatment.

Donor-conceived person
Donor conception

Someone conceived using donated eggs, sperm or embryos.

Donor-conceived person access to information
Donor conception

The rights of donor-conceived people to request information from the HFEA.

Down-Regulation
IVF & treatment

Temporarily switching off the natural hormone cycle before IVF stimulation.

E

Early miscarriage
Pregnancy loss

Pregnancy loss in the first 12 to 13 weeks.

Early pregnancy unit (EPU)
Pregnancy after fertility treatment

An NHS service assessing problems in early pregnancy.

Ectopic Pregnancy
Pregnancy after fertility treatment

A pregnancy implanted outside the uterus.

Egg collection
IVF & treatment

The procedure to collect eggs during IVF.

Egg collection sedation
IVF & treatment

Medication given to keep you comfortable during egg collection.

Egg freezing
Fertility preservation

Collecting and vitrifying eggs for future use.

Egg quality
IVF & treatment

How likely an egg is to fertilise and develop into a healthy embryo.

Egg sharing
Donor conception

Donating some of your eggs during your own IVF in return for reduced-cost treatment.

Elective freeze-all
Treatment add-ons

Freezing all embryos for everyone, even without a medical reason.

Embryo
Embryology

A fertilised egg during early development.

Embryo arrest
Embryology

When an embryo stops developing in the laboratory.

Embryo biopsy
Genetics & PGT

Removing a few cells from an embryo for genetic testing.

Embryo culture
Embryology

Growing embryos in an incubator in the laboratory.

Embryo degeneration
Embryology

An embryo whose cells break down and can no longer develop.

Embryo donation
Donor conception

Donating embryos created during your own IVF so another person can use them.

Embryo fragmentation
Embryology

Small pieces of cell material that break off in early embryos.

Embryo freezing
Fertility preservation

Vitrifying embryos created through IVF for later transfer.

Embryo Grading
Embryology

A visual score for embryo quality.

Embryo selection
Embryology

Choosing which embryo to transfer or freeze first.

Embryo storage
UK regulation & HFEA

Keeping frozen embryos in a licensed centre.

Embryo survival after warming
Frozen embryo transfer

Whether a frozen embryo remains viable once warmed.

Embryo symmetry
Embryology

How evenly sized the cells of an early embryo are.

Embryo Transfer
IVF & treatment

Placing an embryo into the uterus.

Embryo transfer catheter
IVF & treatment

The thin, soft tube used to place an embryo into the uterus.

Embryo warming
Frozen embryo transfer

Thawing a vitrified embryo in the laboratory before transfer.

EmbryoGlue
Treatment add-ons

A transfer medium enriched with hyaluronate.

Embryologist
Embryology

A scientist specialising in embryo development.

Endometrial polyp
Female fertility

A small overgrowth of the uterine lining.

Endometrial preparation
Frozen embryo transfer

Getting the uterine lining ready for an embryo transfer.

Endometrial receptivity testing (ERA)
Treatment add-ons

Endometrial receptivity analysis.

Endometrial scratch
Treatment add-ons

Deliberately irritating the uterine lining before a transfer.

Endometrial thickness
Frozen embryo transfer

How thick the uterine lining measures on ultrasound.

Endometrioma
Female fertility

An ovarian cyst caused by endometriosis.

Endometriosis
Female fertility

Uterine-lining-like tissue growing outside the uterus.

Endometrium
Anatomy & hormones

The lining of the uterus.

Epididymis
Male fertility

A coiled tube behind each testis where sperm mature.

Euploid embryo
Genetics & PGT

An embryo tested as having the expected number of chromosomes.

Exercise and fertility
Lifestyle & preconception

How physical activity relates to fertility.

Expanded blastocyst
Embryology

A blastocyst whose fluid cavity has grown and thinned the shell.

Extended embryo culture
Embryology

Growing embryos to the blastocyst stage (day 5 or 6).

F

Fallopian Tube
Anatomy & hormones

The tube connecting the ovary to the uterus.

Fecundability
Fertility basics

The chance of conceiving in a single menstrual cycle.

Fecundity
Fertility basics

The biological capacity to produce a live birth.

Female-factor infertility
Female fertility

Infertility where a cause relates to the ovaries, tubes or uterus.

Fertile window
Fertility basics

The days in each cycle when sex can lead to pregnancy.

Fertilisation
Embryology

Fusion of sperm and egg.

Fertilisation rate
IVF & treatment

The proportion of mature eggs that fertilise normally.

Fertility
Fertility basics

The ability to conceive a pregnancy and have a baby.

Fertility clinic
Costs & clinic terminology

A centre providing fertility investigations and treatment.

Fertility clinic inspection
UK regulation & HFEA

The HFEA's regular review of licensed clinics.

Fertility medication
Medicines

Medicines used to stimulate the ovaries, control timing or support the lining.

Fertility preservation
Fertility preservation

Freezing eggs, sperm, embryos or tissue to allow the chance of having children later.

Fertility specialist
Fertility basics

A doctor specialising in reproductive medicine.

Fertility treatment add-on
Treatment add-ons

An optional extra offered on top of standard treatment.

Fibroid
Female fertility

A non-cancerous growth of muscle in or around the uterus.

Foetal heartbeat
Pregnancy after fertility treatment

Cardiac activity seen on an early pregnancy scan.

Folic acid
Lifestyle & preconception

A B vitamin that reduces the risk of neural tube defects.

Follicle
Menstrual cycle & ovulation

A fluid-filled sac in the ovary containing an egg.

Follicle-stimulating hormone (FSH)
Anatomy & hormones

Follicle Stimulating Hormone.

Follicular phase
Menstrual cycle & ovulation

The first part of the cycle, when a follicle grows before ovulation.

Freeze-all cycle
IVF & treatment

An IVF cycle in which all suitable embryos are frozen and none transferred fresh.

Fresh cycle
Costs & clinic terminology

A treatment cycle including stimulation, egg collection and usually a fresh transfer.

Fresh embryo transfer
IVF & treatment

Transferring an embryo in the same cycle as egg collection.

Frozen cycle
Costs & clinic terminology

A cycle in which a previously frozen embryo is warmed and transferred.

Frozen embryo transfer (FET)
Frozen embryo transfer

Frozen Embryo Transfer.

G

H

Hatched blastocyst
Embryology

A blastocyst that has fully left its shell.

Hatching blastocyst
Embryology

A blastocyst starting to break out of its shell.

hCG trigger
Medicines

A trigger injection using hCG to mature eggs before collection.

Heat exposure and sperm
Lifestyle & preconception

How raised scrotal temperature can affect sperm production.

Heterotopic pregnancy
Pregnancy after fertility treatment

A pregnancy in the uterus and an ectopic pregnancy at the same time.

HFEA licence
UK regulation & HFEA

Permission granted by the HFEA for a centre to carry out specific activities.

HFEA Register
UK regulation & HFEA

The HFEA's confidential record of licensed treatments, donors and births.

HFEA treatment add-on rating
Treatment add-ons

The HFEA's traffic-light style summary of evidence for each add-on.

HFEA-licensed clinic
UK regulation & HFEA

A UK clinic licensed by the HFEA to provide regulated treatments.

High ovarian response
IVF & treatment

When many follicles develop during stimulation.

hMG (human menopausal gonadotrophin)
Medicines

Human menopausal gonadotrophin — an injectable containing both FSH and LH activity.

Human chorionic gonadotrophin (hCG)
Anatomy & hormones

Human Chorionic Gonadotrophin.

Human Fertilisation and Embryology Authority (HFEA)
UK regulation & HFEA

The UK regulator of fertility treatment.

Hydrosalpinx
Female fertility

A fluid-filled fallopian tube.

Hyperprolactinaemia
Female fertility

Elevated levels of prolactin.

Hyperstimulation
IVF & treatment

Excessive ovarian response to stimulation.

Hypothalamic amenorrhoea
Menstrual cycle & ovulation

Periods stop because the brain reduces its hormone signals to the ovaries.

Hypothalamus
Anatomy & hormones

The part of the brain that starts the hormonal signals controlling fertility.

Hypothyroidism
Female fertility

Underactive thyroid gland.

Hysterosalpingo-contrast sonography (HyCoSy)
Fertility testing

An ultrasound test that checks the fallopian tubes using a contrast fluid.

Hysterosalpingogram (HSG)
Fertility testing

Hysterosalpingogram — X-ray of the uterus and tubes.

Hysteroscopy
Fertility testing

Looking inside the uterus with a thin camera passed through the cervix.

I

Identifying donor information
Donor conception

Details that can identify a donor, such as name and last known address.

Identity-release donor
Donor conception

A donor whose identifying details can be requested by donor-conceived adults.

Immature oocyte
Embryology

An egg not yet ready to be fertilised.

Implantation
Pregnancy after fertility treatment

The embryo embedding into the uterine lining.

Implantation rate
Pregnancy after fertility treatment

The proportion of transferred embryos that implant.

Implantation window
Frozen embryo transfer

The limited time in each cycle when the lining is receptive to an embryo.

Imported donor eggs
Donor conception

Frozen donor eggs from an overseas bank used at a UK clinic.

Imported donor sperm
Donor conception

Donor sperm from an overseas bank used at a UK clinic.

IMSI
Treatment add-ons

ICSI with high-magnification sperm selection.

In vitro fertilisation (IVF)
IVF & treatment

In Vitro Fertilisation.

Infectious-disease screening
Fertility testing

Blood tests for infections such as HIV and hepatitis before treatment.

Infertility
Fertility basics

Not conceiving after regular unprotected sex for a year or longer.

Informed consent
UK regulation & HFEA

Agreeing to treatment after understanding its purpose, risks and alternatives.

Inherited condition
Genetics & PGT

A health condition passed down through genes.

Injection pen
Medicines

A multi-dose device for self-injecting fertility medicines.

Inner cell mass (ICM)
Embryology

The cluster of cells inside a blastocyst that becomes the baby.

Integrated Care Board (ICB)
NHS & fertility access

The NHS body that plans and funds local health services in England.

Intended parent
Surrogacy

A person who plans to raise a child born through surrogacy.

Intracytoplasmic sperm injection (ICSI)
IVF & treatment

Intracytoplasmic Sperm Injection.

Intralipids
Treatment add-ons

A fat emulsion given by drip, promoted to modify immune response.

Intramural fibroid
Female fertility

A fibroid within the muscular wall of the uterus.

Intramuscular Injection
Medicines

An injection given into a muscle.

Intrauterine insemination (IUI)
IVF & treatment

Intrauterine Insemination.

IVF cycle
IVF & treatment

One complete round of IVF, from starting medication to transfer or freezing.

K

L

M

Male-factor infertility
Male fertility

Infertility where a cause relates to sperm or the male reproductive system.

Maternal age
Fertility basics

The age of the person providing the eggs or carrying the pregnancy.

Mature oocyte
Embryology

An egg that has reached the stage where it can be fertilised.

Medical fertility preservation
Fertility preservation

Preservation because a medical treatment or condition may affect fertility.

Medicated (HRT) FET cycle
Frozen embryo transfer

A medicated frozen embryo transfer protocol.

Medication cost
Costs & clinic terminology

The price of fertility medicines, often charged separately.

Medication storage
Medicines

Keeping fertility medicines at the correct temperature.

Meiosis
Genetics & PGT

The cell division that produces eggs and sperm with half the usual chromosomes.

Menotrophin
Medicines

Another name for human menopausal gonadotrophin (hMG).

Menstrual cycle
Menstrual cycle & ovulation

The monthly hormonal cycle that prepares an egg and the uterine lining.

MESA
Male fertility

Microsurgical epididymal sperm aspiration.

Metaphase I (MI)
Embryology

An intermediate egg stage between GV and mature.

Metaphase II (MII)
Embryology

The mature egg stage, ready for fertilisation.

Metformin
Medicines

A diabetes medicine sometimes used in PCOS.

Micro-TESE
Male fertility

Microsurgical TESE using an operating microscope.

Microbiome testing
Treatment add-ons

Testing bacteria in the vagina or uterus to guide treatment.

Mid-luteal progesterone
Fertility testing

A blood test about a week before a period to check whether ovulation happened.

Mild IVF
IVF & treatment

IVF using lower doses of stimulation medicines.

Miscarriage
Pregnancy loss

Pregnancy loss before 24 weeks.

Missed miscarriage
Pregnancy loss

A pregnancy that has stopped developing without bleeding or pain.

Mittelschmerz
Menstrual cycle & ovulation

One-sided pelvic pain some people feel around ovulation.

Mock embryo transfer
IVF & treatment

A practice transfer with no embryo, to check the route into the uterus.

Modified natural-cycle FET
Frozen embryo transfer

A natural-cycle FET that uses a trigger injection or some medication to time ovulation.

Morula
Embryology

A compact ball of cells formed around day 4.

Mosaic embryo
Genetics & PGT

An embryo in which the biopsy showed a mix of normal and abnormal cells.

Multi-cycle package
Costs & clinic terminology

A package covering several IVF cycles for a set price.

Multiple pregnancy
Pregnancy after fertility treatment

Being pregnant with twins, triplets or more.

N

O

Obstructive azoospermia
Male fertility

No sperm in the ejaculate because of a blockage.

Oestradiol
Fertility testing

The main form of oestrogen, measured in blood tests during treatment.

Oestrogen
Anatomy & hormones

A group of hormones that build the uterine lining and regulate the cycle.

Oligo-ovulation
Menstrual cycle & ovulation

Ovulating infrequently or irregularly.

Oligoasthenoteratozoospermia (OAT)
Male fertility

Low count, reduced movement and fewer normally shaped sperm together.

Oligomenorrhoea
Menstrual cycle & ovulation

Infrequent periods, usually cycles longer than 35 days.

Oligozoospermia
Male fertility

A lower sperm count than the reference range.

Oncofertility
Fertility preservation

Fertility care for people with cancer.

Ongoing pregnancy
Pregnancy after fertility treatment

A pregnancy continuing beyond the early weeks, often past 10 to 12 weeks.

Ongoing pregnancy rate
Pregnancy after fertility treatment

The proportion of cycles or transfers leading to an ongoing pregnancy.

Oocyte
Embryology

An egg cell.

Ovarian hyperstimulation syndrome (OHSS)
IVF & treatment

Ovarian Hyperstimulation Syndrome.

Ovarian Reserve
Female fertility

The remaining pool of eggs in the ovaries.

Ovarian stimulation
IVF & treatment

IVF injectable phase to grow multiple follicles.

Ovarian tissue cryopreservation
Fertility preservation

Freezing strips of ovarian tissue for later re-implantation.

Ovary
Anatomy & hormones

One of two organs that store eggs and produce oestrogen and progesterone.

Ovulation
Menstrual cycle & ovulation

Release of a mature egg from the ovary.

Ovulation Induction
IVF & treatment

Medication to stimulate ovulation.

Ovulation predictor kit (OPK)
Menstrual cycle & ovulation

A home urine test that detects the LH surge.

Ovulation tracking
Menstrual cycle & ovulation

Monitoring signs, tests or scans to identify when ovulation occurs.

Oxidative stress
Male fertility

An imbalance that can damage sperm cells and their DNA.

P

Parental order
Surrogacy

A court order transferring legal parenthood from the surrogate to the intended parents.

Parenthood consent
UK regulation & HFEA

Consent forms that give an unmarried partner legal parenthood after licensed treatment.

Paternal age
Fertility basics

The age of the sperm provider.

Pelvic inflammatory disease (PID)
Female fertility

Infection of the upper reproductive tract.

Per-cycle success rate
Costs & clinic terminology

Success measured per cycle started or per egg collection.

Per-transfer success rate
Costs & clinic terminology

Success measured per embryo transfer procedure.

PESA
Male fertility

Percutaneous epididymal sperm aspiration — collecting sperm from the epididymis with a needle.

PGT-A
Genetics & PGT

Preimplantation genetic testing for aneuploidy.

PGT-M
Genetics & PGT

Preimplantation genetic testing for monogenic conditions.

PGT-SR
Genetics & PGT

Preimplantation genetic testing for structural rearrangements.

PICSI
Treatment add-ons

Physiologic ICSI using hyaluronic acid binding.

Pituitary Gland
Anatomy & hormones

A small gland at the base of the brain.

Polar body
Embryology

A small cell released by the egg during maturation.

Polycystic ovary syndrome (PCOS)
Female fertility

Polycystic Ovary Syndrome.

Poor ovarian response
IVF & treatment

When the ovaries produce fewer follicles than expected during stimulation.

Positive pregnancy test
Pregnancy after fertility treatment

A urine or blood test detecting hCG after treatment.

Posthumous use of sperm, eggs or embryos
UK regulation & HFEA

Using gametes or embryos after the person who provided them has died.

Pre-filled syringe
Medicines

A single-dose syringe supplied ready to inject.

Preconception
Fertility basics

The time before trying to conceive or starting treatment.

Preconception care
Lifestyle & preconception

Health steps before pregnancy to support you and a future baby.

Pregnancy loss
Pregnancy loss

The end of a pregnancy that does not result in a live birth.

Pregnancy of unknown location (PUL)
Pregnancy after fertility treatment

A positive test where the pregnancy cannot yet be seen on scan.

Pregnancy tissue testing
Pregnancy loss

Laboratory testing of pregnancy tissue, often to look at chromosomes.

Preimplantation genetic testing (PGT)
Genetics & PGT

Testing cells from IVF embryos before transfer.

Premature ovarian insufficiency (POI)
Female fertility

Loss of normal ovarian function before the age of 40.

Premature ovulation
IVF & treatment

Ovulation happening before planned egg collection.

Primary infertility
Fertility basics

Difficulty conceiving when there has been no previous pregnancy.

Private fertility treatment
NHS & fertility access

Treatment you pay for yourself at a licensed clinic.

Products of conception
Pregnancy loss

Medical term for pregnancy tissue after a miscarriage.

Progesterone
Anatomy & hormones

A hormone that supports the uterine lining.

Progesterone injection
Medicines

Progesterone given by subcutaneous or intramuscular injection.

Progesterone pessary
Medicines

Progesterone inserted into the vagina or rectum for luteal support.

Progressive motility
Male fertility

Sperm moving actively forward.

Prolactin
Fertility testing

A pituitary hormone involved in reproduction and lactation.

Pronucleus
Embryology

The nucleus from the egg or the sperm visible after fertilisation.

Prostate gland
Male fertility

A gland below the bladder that adds fluid to semen.

PRP fertility treatment
Treatment add-ons

Platelet-rich plasma injected into the ovaries or uterus.

Published treatment price
Costs & clinic terminology

The price a clinic advertises for a treatment.

R

S

Saline infusion sonohysterography
Fertility testing

An ultrasound with saline to outline the inside of the uterus.

Same-sex family building
Inclusive family building

Routes to parenthood for same-sex couples.

Scrotum
Male fertility

The skin pouch holding the testes.

Secondary care referral
NHS & fertility access

A referral from primary care (your GP) to a hospital or specialist clinic.

Secondary infertility
Fertility basics

Difficulty conceiving after a previous pregnancy.

Semen
Male fertility

The fluid ejaculated, containing sperm and fluids from the glands.

Semen Analysis
Fertility testing

A test of sperm count, motility and morphology.

Seminal vesicle
Male fertility

Glands that produce most of the fluid in semen.

Seminiferous tubules
Male fertility

Tiny tubes inside the testes where sperm are made.

Sharps bin
Medicines

A puncture-proof container for used needles.

Short protocol
IVF & treatment

An IVF protocol that starts stimulation at the beginning of the cycle.

Single Embryo Transfer
IVF & treatment

Transferring one embryo at a time.

Sleep and fertility
Lifestyle & preconception

The relationship between sleep and reproductive health.

Smoking and fertility
Lifestyle & preconception

How smoking affects the chances of conceiving.

Solo parenthood by choice
Inclusive family building

Choosing to become a parent without a partner.

Sperm
Male fertility

The male reproductive cell that fertilises an egg.

Sperm concentration
Male fertility

The number of sperm per millilitre of semen.

Sperm DNA Fragmentation
Male fertility

Damage to DNA within sperm.

Sperm freezing
Fertility preservation

Storing sperm samples at very low temperatures.

Sperm morphology
Male fertility

Shape of sperm.

Sperm motility
Male fertility

Movement of sperm.

Sperm vitality
Male fertility

The proportion of sperm that are alive.

Spermatogenesis
Male fertility

The process of producing sperm in the testes.

Spotting
Menstrual cycle & ovulation

Light bleeding outside a normal period.

Steroids in fertility treatment
Treatment add-ons

Using corticosteroids such as prednisolone during treatment.

Stillbirth
Pregnancy loss

When a baby dies in the womb after 24 weeks of pregnancy.

Storage fee
Costs & clinic terminology

The ongoing charge for keeping eggs, sperm or embryos frozen.

Storage period
UK regulation & HFEA

How long eggs, sperm or embryos may lawfully be stored.

Storage renewal
UK regulation & HFEA

Confirming you want stored material kept for a further period.

Stress and fertility
Lifestyle & preconception

How stress relates to trying to conceive and treatment.

Subcutaneous Injection
Medicines

An injection given into the fatty layer just under the skin.

Subfertility
Fertility basics

Reduced fertility — taking longer than expected to conceive.

Submucosal fibroid
Female fertility

A fibroid bulging into the uterine cavity.

Subserosal fibroid
Female fertility

A fibroid on the outer surface of the uterus.

Surgical sperm retrieval (SSR)
Male fertility

Surgical Sperm Retrieval.

Surrogacy
Surrogacy

When someone carries a pregnancy for intended parents.

Surrogacy agreement
Surrogacy

An arrangement setting out the intentions of surrogate and intended parents.

Surrogate
Surrogacy

The person who carries a pregnancy for intended parents.

T

Ten-family donor limit
Donor conception

The UK limit on how many families one donor can help create.

Teratozoospermia
Male fertility

A low percentage of normally shaped sperm.

TESA
Male fertility

Testicular sperm aspiration — collecting sperm from the testis with a needle.

TESE
Male fertility

Testicular sperm extraction — removing small samples of testicular tissue to find sperm.

Testicular tissue freezing
Fertility preservation

Freezing testicular tissue, mainly for boys before puberty.

Testis
Male fertility

One of two glands producing sperm and testosterone.

Testosterone
Anatomy & hormones

The primary male sex hormone.

Thyroid Function Test
Fertility testing

Blood test measuring thyroid hormones.

Time-lapse Imaging
Treatment add-ons

Continuous imaging of embryos in the incubator.

Total fertilisation failure
Embryology

When none of the eggs fertilise in an IVF or ICSI cycle.

Total motile sperm count (TMSC)
Male fertility

The number of moving sperm in the whole sample.

Total sperm count
Male fertility

The total number of sperm in the whole ejaculate.

Traditional surrogacy
Surrogacy

Surrogacy where the surrogate's own egg is used.

Transgender fertility preservation
Inclusive family building

Freezing eggs, sperm or tissue before gender-affirming treatment.

Transvaginal ultrasound
Fertility testing

An internal ultrasound using a slim probe in the vagina.

Treatment package
Costs & clinic terminology

A bundle of treatment steps sold for one price.

Treatment quote
Costs & clinic terminology

A written estimate of the cost of your personal treatment plan.

Trigger Injection
Medicines

Injection that matures eggs before collection.

Triple-line endometrium
Frozen embryo transfer

A layered appearance of the lining on ultrasound before ovulation or progesterone.

Trophectoderm
Embryology

The outer layer of a blastocyst.

Trying to conceive (TTC)
Fertility basics

Actively trying to become pregnant.

Tubal-factor infertility
Female fertility

Infertility caused by damaged or blocked fallopian tubes.

Two pronuclei (2PN)
Embryology

The sign of normal fertilisation checked the day after egg collection.

Two Week Wait
IVF & treatment

The wait between transfer and pregnancy test.

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