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Fertility Glossary

Total fertilisation failure

When none of the eggs fertilise in an IVF or ICSI cycle.

Embryology

Total fertilisation failure is uncommon but very distressing. Your clinic should review possible reasons — egg, sperm or laboratory factors — and discuss options such as ICSI or other approaches in a future cycle.

Also known as: failed fertilisation, TFF, fertilisation failure

Related United Kingdom guides

Last reviewed: 23 September 2026. Written by the Antega Editorial Team. General information only — always follow the advice of your own clinic, doctor or pharmacist.

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